168102-90-7

Upstream product

• 67-56-1 methanol 
• 188640-86-0 (R)-1-((3aS,5R,6R,6aS)-6-Benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-but-3-yn-1-ol 
• 100-44-7 benzyl chloride 
• 168103-00-2 (((3aS,5R,6R,6aS)-6-(benzyloxy)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methoxy)(tert-butyl)diphenylsilane 
• 19139-80-1 ((3aS,5R,6R,6aS)-6-(benzyloxy)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methanol 
• 114738-04-4 (3aS,5R,6R,6aS)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol 
• 110316-24-0 3-O-benzyl-1,2-O-isopropylidene-β-D-arabino-pentodialdo-1,4-furanose 

Downstream Products

• 168102-92-9 3-O-benzyl-6-deoxy-1,2-O-isopropylidene-β-D-altro-heptofuranose 

Relevant academic research and scientific papers

Diastereoselective propargylation of sugar aldehydes. New synthesis of 6-deoxyheptoses

Propargylation of pentofuranose aldehydes by treatment with propargyl bromide in the presence of zinc dust yielded homopropargylic alcohols with a good isolated yield and, in many cases, excellent anti/syn selectivity. Catalytic hydrogenation of the triple bond afforded homoallylic alcohols, valuable substrates for the synthesis of 6-deoxyheptoses. Direct ozonolysis of the triple bond yielded uronic acid esters.

The Raction of Acetyliron 5-C5H5)Fe(CO)(PPh3)(COCH3)> with Sugar Aldehydes. New Synthesis of Deoxysugars

Aldol reactions of sugar aldehydes (5-13) with enolate 2 of racemic and both enantiomeric forms of acetyliron were investigated.The steric course of reactions depended strongly on the counterions used.High stereocontrol was achieved with the following cat