168172-74-5

Upstream product

• 1122-58-3 dmap 
• 2244-59-9 8-chloro-10,11-dihydrodibenz[b,f][1,4]oxazepine 
• 98-58-8 4-bromobenzenesulfonyl chloride 

Downstream Products

• 168172-75-6 8-chloro-10,11-dihydro-10-[[4-[(4-pyridinyl)ethynyl]phenyl]sulfonyl]dibenz[b,f][1,4]-oxazepine 
• 168172-89-2 3-[(8-chlorodibenz[b,f][1,4]oxazepin-10(11H)-yl)carbonyl]-N-(4-pyridinylmethyl)benzamide, monohydrochloride 
• 168172-77-8 4-[(8-chlorodibenz[b,f][1,4]oxazepin-10(11H)-yl)sulfonyl]-N-(4-pyridinylmethyl)benzamide, monohydrochloride 

Relevant academic research and scientific papers

Aryl substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use

The present invention provides substituted dibenzoxazepine compounds of Formula I: STR1 which are useful as analgesic agents for the treatment of pain, and for the treatment of prostaglandin E2 -mediated diseases, pharmaceutical compositions comprising a therapeutically-effective amount of a compound of Formula I in combination with a pharmaceutically-acceptable carrier, a method for eliminating or ameliorating pain in an animal, and a method for treating prostaglandin E2 -mediated diseases in an animal, comprising administering a therapeutically-effective amount of a compound of Formula I to the animal.