168279-54-7

Basic information

• Product Name: ETHYL 3-(METHYLTHIO)-4-OXO-4,5,6,7-TETRAHYDROBENZO[C]THIOPHENE-1-CARBOXYLATE
• Synonyms: ETHYL 3-(METHYLTHIO)-4-OXO-4,5,6,7-TETRAHYDROBENZO[C]THIOPHENE-1-CARBOXYLATE;BUTTPARK 33\04-64;RARECHEM AK MA K006;ethyl 3-(Methylsulfanyl)-4-oxo-4,5,6,7-tetrahydro-2- benzothiophene-1-carboxylate;Ethyl 3-(methylsulphanyl)-4-oxo-4,5,6,7-tetrahydrobenzo[c]thiophene-1-carboxylate;Ethyl 3-(methylthio)-4-oxo-4,5,6,7-tetrahydrobenzo[c]thiophene-1-carboxylate, Ethyl 3-(methylsulphanyl)-4-oxo-4,5,6,7-tetrahydro-2-benzothiophene-1-carboxylate;Tetrahydro-3-methylthio-4-oxobenzo[c]thiophene-1-carboxylic acid ethylester;Benzo[c]thiophene-1-carboxylic acid, 4,5,6,7-tetrahydro-3-(methylthio)-4-oxo-, ethyl ester
• CAS NO: 168279-54-7
• Molecular Formula: C₁₂H₁₄O₃S₂
• Molecular Weight: 270.37
• Mol File: 168279-54-7.mol
• Article Data: 6

Chemical Properties

• Melting Point: 108 °C
• Boiling Point: 446.1°C at 760 mmHg
• Flash Point: 223.6°C
• Appearance: /
• Density: 1.31g/cm³
• Vapor Pressure: 3.74E-08mmHg at 25°C
• Refractive Index: 1.594
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: ETHYL 3-(METHYLTHIO)-4-OXO-4,5,6,7-TETRAHYDROBENZO[C]THIOPHENE-1-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 3-(METHYLTHIO)-4-OXO-4,5,6,7-TETRAHYDROBENZO[C]THIOPHENE-1-CARBOXYLATE(168279-54-7)
• EPA Substance Registry System: ETHYL 3-(METHYLTHIO)-4-OXO-4,5,6,7-TETRAHYDROBENZO[C]THIOPHENE-1-CARBOXYLATE(168279-54-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 168279-54-7(Hazardous Substances Data)

Usage

General Description

ETHYL 3-(METHYLTHIO)-4-OXO-4,5,6,7-TETRAHYDROBENZO[C]THIOPHENE-1-CARBOXYLATE is a chemical compound that belongs to the class of carboxylic esters. It contains a benzothiophene ring with a methylthio group and an ethyl ester functional group. The compound is characterized by its four-carbon heterocyclic ring with a sulfur atom, and a ketone group at position 4. It is commonly used in organic synthesis and pharmaceutical research. The compound may have potential applications in the development of pharmaceuticals due to its structural features and reactivity.

InChI:InChI=1/C12H14O3S2/c1-3-15-11(14)10-7-5-4-6-8(13)9(7)12(16-2)17-10/h3-6H2,1-2H3

Upstream product

• 75-15-0 carbon disulfide 
• 504-02-9 1,3-cylohexanedione 
• 105-36-2 ethyl bromoacetate 
• 74-88-4 methyl iodide 
• 105-39-5 chloroacetic acid ethyl ester 

Downstream Products

• 168279-57-0 3-methylthio-5,6,7,8-tetrahydro benzothiophene-4-one 
• 175202-53-6 Ethyl 6,7-dihydro-3-(methylthio)benzothiophene-1-carboxylate 
• 848127-23-1 3-methylsulfanyl-1-[4-(4-nitro-phenyl)-5-thioxo-4,5-dihydro-1H-[1,2,4]triazol-3-yl]-6,7-dihydro-5H-benzo[c]thiophen-4-one 
• 848127-22-0 1-(4-cyclohexyl-5-thioxo-4,5-dihydro-1H-[1,2,4]triazol-3-yl)-3-methylsulfanyl-6,7-dihydro-5H-benzo[c]thiophen-4-one 
• 848127-24-2 1-[4-(4-methoxy-phenyl)-5-thioxo-4,5-dihydro-1H-[1,2,4]triazol-3-yl]-3-methylsulfanyl-6,7-dihydro-5H-benzo[c]thiophen-4-one 

Relevant articles and documents

Synthesis of new 3-methylthio-4,5,6,7-tetrahydro benzo[c]thiophene-4-ones

A new route to 1,3-disubstituted-4,5,6,7-tetrahydro benzo[c]thiophene-4-one is described starting from 1,3-cyclohexanedione.

COMPOUNDS AND COMPOSITIONS FOR TREATING FIBROSIS

The present invention provides compounds and methods for treating MKP-5 modulated disease. In certain embodiments, the MKP-5 modulated disease is a fibrotic disease.

FUSED HETEROCYCLIC COMPOUND

The present invention provides a fused heterocyclic compound that has CDK 8 and/or CDK 19 inhibitory activity. The present invention provides a compound represented by formula (I) (wherein the symbols are as defined in the description) or a salt thereof.