168332-91-0

Upstream product

• 31536-21-7 isopropyl 4-methylbenzenesulfinate 
• 693-02-7 hex-1-yne 
• 69393-87-9 1-(hex-1-ynylsulfanyl)-4-methylbenzene 

Downstream Products

• 30506-35-5 butyl(p-tolyl)sulfoxide 
• 71964-05-1 (E)-1-(hex-1-en-1-ylsulfonyl)-4-methylbenzene 
• 6378-07-0 ethyl (p-tolyl)sulfoxide 

Relevant academic research and scientific papers

Studies on hydrozirconation of 1-alkynyl sulfoxides or sulfones and the application for the synthesis of stereodefined vinyl sulfoxides or sulfones

The hydrozirconation reaction of 1-alkynyl sulfoxides or sulfones with CP2Zr(H)Cl in THF at room temperature predominantly gave Z-β-zirconated vinyl sulfoxides or sulfones with excellent regioselectivity. Compared with 1-alkynyl sulfoxides, the hydrozirconation reaction of 1-alkynyl sulfones exhibits great synthetic potential, leading to the efficient preparation of Z-β-halovinyl sulfones, Z-β-sulfonyl α,β-unsaturated ketones, and Z-β-alkynyl vinyl sulfones. Although the reaction mechanisms are still not clear, the neighboring group participation of the sulfinyl or sulfonyl group may be playing an important role in this unique hydrozirconation reaction.

A selective and convenient oxidation of acetylenic sulfides to acetylenic sulfoxides using trichloroisocyanuric acid

Acetylenic sulfides are readily oxidized to acetylenic sulfoxides by a solution of pyridine, water, benzoic acid and trichloroisocyanuric acid in acetonitrile and methylene chloride.