168414-39-9Relevant academic research and scientific papers
(Aryloxy)methylsilane Derivatives as New Cholesterol Biosynthesis Inhibitors: Synthesis and Hypocholesterolemic Activity of a New Class of Squalene Epoxidase Inhibitors
Gotteland, Jean-Pierre,Brunel Isabelle,Gendre, Fabrice,Desire, Jerome,Delhon, Andre,at al.
, p. 3207 - 3216 (2007/10/03)
A series of 3-substituted (aryloxy)silane derivatives of benzylamine (4' 4', or 4") was synthesized and evaluated for hypocholesterolemic activity.Most of the new silane derivatives were identified as potent inhibitors of pig liver squalene epoxidase with
