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Xanthomegnin is a napthoquinone mycotoxin, a type of chemical compound derived from fungi. It is known for its presence in the epidermis, which can be utilized for diagnostic purposes in certain medical conditions.

1685-91-2

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Basic information
1. Product Name: xanthomegnin
2. Synonyms: xanthomegnin;(3R,3'R)-3,3',4,4'-Tetrahydro-10,10'-dihydroxy-7,7'-dimethoxy-3,3'-dimethyl-8,8'-bi[1H-naphtho[2,3-c]pyran]-1,1',6,6',9,9'-hexone;(3R,3'R)-3,3'-Dimethyl-7,7'-dimethoxy-10,10'-dihydroxy-3,3',4,4'-tetrahydro-8,8'-bi[1H-naphtho[2,3-c]pyran]-1,1',6,6',9,9'-hexone;Xanthomegnine;NSC 264720
3. CAS NO:1685-91-2
4. Molecular Formula: C₃₀H₂₂O₁₂
5. Molecular Weight: 574.492
6. EINECS: N/A
7. Product Categories: N/A
8. Mol File: 1685-91-2.mol
Chemical Properties
1. Melting Point: N/A
2. Boiling Point: 943.7°Cat760mmHg
3. Flash Point: 315.7°C
4. Appearance: /
5. Density: 1.63g/cm³
6. Vapor Pressure: 0mmHg at 25°C
7. Refractive Index: 1.705
8. Storage Temp.: N/A
9. Solubility: N/A
10. CAS DataBase Reference: xanthomegnin(CAS DataBase Reference)
11. NIST Chemistry Reference: xanthomegnin(1685-91-2)
12. EPA Substance Registry System: xanthomegnin(1685-91-2)
Safety Data
1. Hazard Codes: N/A
2. Statements: N/A
3. Safety Statements: N/A
4. WGK Germany:
5. RTECS:
6. HazardClass: N/A
7. PackingGroup: N/A
8. Hazardous Substances Data: 1685-91-2(Hazardous Substances Data)

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1685-91-2 Usage

Uses

Used in Medical Diagnostics:
Xanthomegnin is used as a diagnostic marker for identifying Trichophyton rubrum infections. This application is based on its presence in the epidermis, which can indicate the presence of the fungal infection when detected.

Check Digit Verification of cas no

The CAS Registry Mumber 1685-91-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,6,8 and 5 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1685-91:
(6*1)+(5*6)+(4*8)+(3*5)+(2*9)+(1*1)=102
102 % 10 = 2
So 1685-91-2 is a valid CAS Registry Number.

InChI:InChI=1/C30H22O12/c1-9-5-11-7-13(31)17-19(15(11)29(37)41-9)25(35)27(39-3)21(23(17)33)22-24(34)18-14(32)8-12-6-10(2)42-30(38)16(12)20(18)26(36)28(22)40-4/h7-10,31-32H,5-6H2,1-4H3

1685-91-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name	10-hydroxy-8-(10-hydroxy-7-methoxy-3-methyl-1,6,9-trioxo-3,4-dihydrobenzo[g]isochromen-8-yl)-7-methoxy-3-methyl-3,4-dihydrobenzo[g]isochromene-1,6,9-trione

1.2 Other means of identification

Product number	-
Other names	xanthomegnin

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1685-91-2 SDS

1685-91-2Upstream product

1685-91-2Downstream Products

625-72-9 (R)-3-hydroxybutyric acid

1685-91-2Related news

Short communicationHepatic alterations produced in mice by xanthomegnin (cas 1685-91-2) and viomellein, metabolites of Penicillium viridicatum09/30/2019

Xanthomegnin and viomellein obtained from a toxigenic isolate of Penicillium viridicatum were fed to weanling male Swiss mice at dietary concentrations of 448 and 456 mg/kg of feed, respectively. Gross alterations included jaundice, greenish discoloration of the kidney, and small foci of discolo...detailed

The isolation of xanthomegnin (cas 1685-91-2) from several strains of the dermatophyte, Trichophyton rubrum☆09/29/2019

One of the three pigments isolated in crystalline form from the mycelium of the dermatophyte, Trichophyton rubrum, has been shown to be identical with the pigment, xanthomegnin, previously isolated from T. megnini. Several additional derivatives of the compound are reported.detailed

High-performance liquid chromatographic separation of xanthomegnin (cas 1685-91-2) and viomellein10/01/2019

Preliminary separations of xanthomegnin and viomellein demonstrated some irreversible binding to silica. However, reversed-phase high-performance liquid chromatographic procedures on C18 columns showed that binding could be minimized by the inclusion of sodium dodecyl sulfate in the mobile phase...detailed

2D-PAGE examination of mRNA populations from Pénicillium freii mutants deficient in xanthomegnin (cas 1685-91-2) biosynthesis09/27/2019

Penicillium freii (Lund and Frisvad 1994) mutants deficient in the synthesis of xanthomegnin were isolated. In vitro translated mRNA populations from selected radiation induced mutants and naturally occurring P. freii strains not able to produce xanthomegnin were examined by 2-dimensional polyac...detailed

Studies of the teratogenicity of xanthomegnin (cas 1685-91-2) and viridicatumtoxin in ICR mice09/26/2019

The myotoxins xanthomegnin and viridicatumtoxin were not teratogenic when administered orally to pregnant ICR mice during the 8–12th and 8–13th days of gestation, respectively. Viridicatumtoxin produced high mortality in mice given 200, 250 or 350 mgkg of body weight.detailed

Regular ArticleDetection of xanthomegnin (cas 1685-91-2) in Epidermal Materials Infected with Trichophyton rubrum09/25/2019

Xanthomegnin, a mutagenic mycotoxin best known as an agent of nephropathy and death in farm animals exposed to food-borne Penicillium and Aspergillus fungi, was first isolated about 35 y ago as a diffusing pigment from cultures of the dermatophyte, Trichophyton megninii. This study investigates ...detailed

xanthomegnin (cas 1685-91-2) detection does not discriminate between Trichophyton rubrum and T. mentagrophytes complexes09/24/2019

Here, we aimed to discriminate the Trichophyton rubrum and Trichophyton mentagrophytes complexes, via detection of xanthomegnin using HPLC. We concluded that it is not a reliable technique for discriminating the two complexes, because strains belonging to both T. rubrum and T. mentagrophytes com...detailed

1685-91-2Relevant academic research and scientific papers

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