16860-34-7Relevant academic research and scientific papers
Nucleophilic substitution of azide acting as a pseudo leaving group: One-step synthesis of various aza heterocycles
Doebelin, Christelle,Schmitt, Martine,Antheaume, Cyril,Bourguignon, Jean-Jacques,Bihel, Frederic
, p. 11335 - 11341 (2013/12/04)
The reaction of 3-azidopropanoic acid with the carbodiimide-based coupling reagent DIC leads to a six-membered-ring intermediate acting as a versatile precursor to a diverse set of aza heterocycles, including mono-, bi-, and tricyclic compounds.
Synthesis and pharmacological characterisation of a conformationally restrained series of indole-2-carboxylates as in vivo potent glycine antagonists
Di Fabio, Romano,Araldi, Gianluca,Baraldi, Davide,Cugola, Alfredo,Donati, Daniele,Gastaldi, Paola,Giacobbe, Simone A,Micheli, Fabrizio,Pentassuglia, Giorgio
, p. 791 - 798 (2007/10/03)
After the identification of GV150526, the indole-2-carboxylate template was further explored in order to identify novel potential anti-stroke agents. In particular, the SAR of the side chain present at the C-3 position of the indole nucleus was widely stu
