16862-05-8

Basic information

• Product Name: Methyl-3-(2-thienyl)=propionate
• Synonyms: Methyl-3-(2-thienyl)=propionate;2-Thiophenepropanoicacid,methylester;3-(Thiophen-2-yl)propionic Acid Methyl Ester;Methyl 3-(thiophen-2-yl)propanoate
• CAS NO: 16862-05-8
• Molecular Formula: C₈H₁₀O₂S
• Molecular Weight: 170.2288
• Product Categories: Aromatics;Sulfur & Selenium Compounds
• Mol File: 16862-05-8.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 228.2 °C at 760 mmHg
• Flash Point: 91.8 °C
• Appearance: /
• Density: 1.148g/cm³
• Vapor Pressure: 0.0744mmHg at 25°C
• Refractive Index: 1.522
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Methyl-3-(2-thienyl)=propionate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl-3-(2-thienyl)=propionate(16862-05-8)
• EPA Substance Registry System: Methyl-3-(2-thienyl)=propionate(16862-05-8)

Safety Data

• Hazardous Substances Data: 16862-05-8(Hazardous Substances Data)

Usage

Chemical Properties

Colourless Oil

Uses

Methyl 3-[2-Thienyl)propanoate (cas# 16862-05-8) is a compound useful in organic synthesis.

InChI:InChI=1/C8H10O2S/c1-10-8(9)5-4-7-3-2-6-11-7/h2-3,6H,4-5H2,1H3

Upstream product

• 67-56-1 methanol 
• 5928-51-8 3-(2-thienyl)propanoic acid 
• 57502-38-2 methyl (E)-3-(2-thienyl)propenoate 
• 1124-65-8 3-(2-thienyl)-2-propenoic acid 
• 5834-04-8 3-(2-thienyl)-propanoic acid chloride 
• 79-22-1 methyl chloroformate 
• 77998-66-4 C₄H₃S^(1-) 
• 292638-85-8 acrylic acid methyl ester 
• 15690-25-2 3-(2-thienyl)acrylic acid 
• 26359-21-7 3-(thiophen-2-yl)propanal 

Downstream Products

• 5650-51-1 5,6-dihydro-<6H>-cyclopenta--thiophene-4-one 
• 954238-22-3 5,6-dihydro-4H-cyclopenta[b]thiophen-4-ol 
• 133486-21-2 (E)-3-[2-n-butyl-1-{(2-chlorophenyl)methyl}-1H-imidazol-5-yl]-2-(2-thienyl)methyl-2-propenol 
• 133486-11-0 (E)-3-[2-n-butyl-1-[(2-chlorophenyl)methyl]-1H-imidazol-5-yl]-2-(thien-2-yl)methyl-2-propenamide 
• 148674-39-9 SB 206328 
• 149543-80-6 methyl (E)-3-[2-n-butyl-1-{(4-carbomethoxy-3-methoxymethoxyphenyl)methyl}-1H-imidazol-5-yl]-2-(thien-2-yl)methyl-2-propenoate 

Relevant articles and documents

Organopalladium approaches to prostaglandins. I. Synthesis of thiophene-containing prostaglandin endoperoxide analogs via thienylpalladation of bicyclic olefins

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Organopalladium approaches to prostaglandins. 5. Synthesis of bicyclic and tricyclic prostanoic acids and thiophene-containing prostaglandin endoperoxide analogues via thienylpalladation of bicyclic alkenes

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Industrial preparation method of 2-ethylamine-heterocyclic derivative

The invention provides an industrial preparation method of a 2-ethylamine-heterocyclic derivative. The method is characterized in that a heteroaryl derivative and 2-substituent ethylene react to produce a 2-(2-cyanoethyl)-heterocyclic derivative, a 2-acetate-heterocyclic derivative and a 2-(3-butyl ketone)-heterocyclic derivative separately. The production method is simple and different from complicated production modes and harsh production conditions in the prior art. By means of the industrial preparation method, synthesis of a target product can be achieved by one step. As the production technology and synthetic route are optimized through the preparation method, in the production process, few side reactions occur, the aftertreatment is convenient, the production condition is mild, and the preparation method is suitable for an industrialized production mode.

Visible light-induced selective generation of radicals from organoborates by photoredox catalysis

A new strategy for the generation of carbon-centered radicals via oxidation of alkyl-, allyl-, benzyl- and arylborates by visible-light-driven single electron transfer (SET) photoredox catalysis has been established. The generated radicals smoothly react with TEMPO and electron-deficient alkenes to afford C-O and C-C coupling products, respectively. In this radical initiating system, cyclic organo(triol)borates turn out to be useful radical precursors.