168632-98-2

Basic information

• Product Name: 4-Benzyloxycarbonylamino-2,2-difluoro-3-hydroxy-5-phenyl-N-benzylpentanamide
• Synonyms: 4-Benzyloxycarbonylamino-2,2-difluoro-3-hydroxy-5-phenyl-N-benzylpentanamide
• CAS NO: 168632-98-2
• Molecular Weight: 468.5
• Mol File: 168632-98-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-Benzyloxycarbonylamino-2,2-difluoro-3-hydroxy-5-phenyl-N-benzylpentanamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Benzyloxycarbonylamino-2,2-difluoro-3-hydroxy-5-phenyl-N-benzylpentanamide(168632-98-2)
• EPA Substance Registry System: 4-Benzyloxycarbonylamino-2,2-difluoro-3-hydroxy-5-phenyl-N-benzylpentanamide(168632-98-2)

Safety Data

• Hazardous Substances Data: 168632-98-2(Hazardous Substances Data)

Upstream product

• 59830-60-3 N-benzyloxycarbonyl-2-amino-3-phenylpropionaldehyde 
• 100-46-9 benzylamine 

Downstream Products

• 184709-55-5 [1-[(1-benzyl-3-benzylcarbamoyl-3,3-difluoro-2-oxo-propylcarbamoyl)-methyl]-2-(4-fluoro-phenyl)-6-oxo-1,6-dihydro-pyrimidin-5-yl]-carbamic acid benzyl ester 
• 1026057-61-3 {1-[(1-benzyl-3-benzylcarbamoyl-3,3-difluoro-2-hydroxy-propylcarbamoyl)-methyl]-6-oxo-2-m-tolyl-1,6-dihydro-pyrimidin-5-yl}-carbamic acid benzyl ester 
• 1026599-48-3 {1-[(1-benzyl-3-benzylcarbamoyl-3,3-difluoro-2-oxo-propylcarbamoyl)-methyl]-6-oxo-2-m-tolyl-1,6-dihydro-pyrimidin-5-yl}-carbamic acid benzyl ester 
• 243462-52-4 2-[5-benzyloxycarbonylamino-2-(3-chlorophenyl)-1,6-dihydro-6-oxo-1-pyrimidinyl]-N-[1-benzyl-3-[N-(benzyl)carbamoyl]-3,3-difluoro-2-oxopropyl]acetamide 
• 243462-51-3 2-[5-benzyloxycarbonylamino-2-(3-chlorophenyl)-1,6-dihydro-6-oxo-1-pyrimidinyl]-N-[1-benzyl-3-[N-(benzyl)carbamoyl]-3,3-difluoro-2-hydroxypropyl]acetamide 
• 1027248-69-6 [1-[(1-benzyl-3-benzylcarbamoyl-3,3-difluoro-2-oxo-propylcarbamoyl)-methyl]-2-(3-fluoro-phenyl)-6-oxo-1,6-dihydro-pyrimidin-5-yl]-carbamic acid benzyl ester 
• 1026878-63-6 [1-[(1-benzyl-3-benzylcarbamoyl-3,3-difluoro-2-hydroxy-propylcarbamoyl)-methyl]-2-(3-fluoro-phenyl)-6-oxo-1,6-dihydro-pyrimidin-5-yl]-carbamic acid benzyl ester 
• 1026583-79-8 {1-[(1-benzyl-3-benzylcarbamoyl-3,3-difluoro-2-oxo-propylcarbamoyl)-methyl]-6-oxo-2-phenyl-1,6-dihydro-pyrimidin-5-yl}-carbamic acid benzyl ester 
• 1026395-17-4 {1-[(1-benzyl-3-benzylcarbamoyl-3,3-difluoro-2-hydroxy-propylcarbamoyl)-methyl]-6-oxo-2-phenyl-1,6-dihydro-pyrimidin-5-yl}-carbamic acid benzyl ester 
• 1027827-18-4 {1-[(1-benzyl-3-benzylcarbamoyl-3,3-difluoro-2-oxo-propylcarbamoyl)-methyl]-6-oxo-2-pyridin-4-yl-1,6-dihydro-pyrimidin-5-yl}-carbamic acid benzyl ester 
• 1026417-77-5 {1-[(1-benzyl-3-benzylcarbamoyl-3,3-difluoro-2-hydroxy-propylcarbamoyl)-methyl]-6-oxo-2-pyridin-4-yl-1,6-dihydro-pyrimidin-5-yl}-carbamic acid benzyl ester 
• 1027180-05-7 {1-[(1-benzyl-3-benzylcarbamoyl-3,3-difluoro-2-oxo-propylcarbamoyl)-methyl]-6-oxo-2-pyridin-3-yl-1,6-dihydro-pyrimidin-5-yl}-carbamic acid benzyl ester 
• 243462-36-4 Y-40018 

Relevant articles and documents

Synthesis, structure - Activity relationships, and pharmacokinetic profiles of nonpeptidic difluoromethylene ketones as novel inhibitors of human chymase

Potent human chymase inhibitors with high enzymatic selectivity and satisfactory metabolic stability were obtained by replacing the Val-Pro (P3-P2) dipeptide portion of the previously described inhibitor 1 with a nonpeptidic pyrimidi