38170-02-4Relevant academic research and scientific papers
A two-photon fluorescent probe for real-time monitoring of autophagy by ultrasensitive detection of the change in lysosomal polarity
Jiang, Jiacheng,Tian, Xiaohe,Xu, Changzhi,Wang, Shuxin,Feng, Yan,Chen, Man,Yu, Haizhu,Zhu, Manzhou,Meng, Xiangming
, p. 3645 - 3648 (2017)
The first two-photon probe, Lyso-OC, was proposed for use in monitoring cell autophagy by detection of the change in the lysosomal polarity during the membrane fusion process of autophagy. The Lyso-OC probe exhibited desirable optical properties and a det
Experimental and DFT studies of disubstituted 2-(2-hydroxyphenyl)benzothiazole-based fluorophores synthesized by Suzuki coupling
Niu, Yahui,Wang, Qin,Wu, Haoran,Wang, Yuxiu,Zhang, Yanrong
, p. 9796 - 9805 (2017)
Among the various fascinating fluorescent compounds, excited-state intramolecular proton transfer (ESIPT) dyes have been drawing much attention due to their anomalously large Stokes shifts. Furthermore, ESIPT fluorophores are attractive as their fluoresce
Breathing Room: Restoring Free Rotation in a Schiff-Base Macrocycle through Endoperoxide Formation
Chaudhry, Mohammad T.,Ota, Seiya,Lelj, Francesco,MacLachlan, Mark J.
supporting information, p. 9538 - 9542 (2021/12/17)
Macrocyclization is a popular method for preparing hosts, but it can have unintended effects, like limiting molecular free rotation to yield mixtures of inseparable isomers. We report a [3 + 3] Schiff-base macrocycle (1) with anthracene bridges. Restricte
Coumarin oxime ester photoinitiator
-
Paragraph 0095-0101, (2019/10/02)
The invention provides a coumarin oxime ester photoinitiator and a preparation method thereof. The molecular structure general formula is shown in the formula (I). The photoinitiator triggers photocuring under the radiation wavelength of 360-450 nm, and is applied to the fields such as single-photon 3D printing, double-photon 3D printing, printing ink and photoresist. The photoinitiator can serveas an LED photoinitiator and a double-photon photoinitiator, good triggering activity is achieved, one photoinitiator has two purposes, and the manufacturing cost is reduced to a certain degree.
Fluorescent 7-Substituted Coumarin Dyes: Solvatochromism and NLO Studies
Bhagwat, Archana A.,Sekar, Nagaiyan
, p. 121 - 135 (2018/11/10)
The effect of three substituents N,N-diethylamine, carbazole and diphenylamine at the 7 position of coumarin on linear and nonlinear optical properties are studied using absorption and emission solvatochromism, and DFT. By varying the substituent 53?nm red shift is achieved in emission. The polarity plots with regression close to unity revealed good charge transfer in the system. Solvent polarizability and dipolarity are mainly responsible for solvatochromic shift as proved by multilinear regression analysis. General Mulliken Hush analysis shows diphenylamine substituent leads to more charge separation in compound 6c. The hyperpolarizabilities are evaluated by quantum mechanical calculations. Structure of the compounds are optimized at B3LYP/6-31G(d) level and NLO computations are done using range separated hybrid functionals with large basis sets. Second order hyperpolarizability (γ) found 589.27 × 10?36, 841.29 × 10?36 and 1043.00 × 10?36 e.s.u for the compounds 6a, 6b and 6c respectively.
A seven substituted coumarin derivatives of two-photon fluorescent dye and its preparation method
-
Paragraph 0022; 0023; 0024, (2017/03/17)
The invention discloses 7-substituted coumarin derivative two-photon fluorescent dye. The structural formula is as shown in the specification, wherein R is CH3O- or (CH3)2N-. The fluorescent dye disclosed by the invention is simple to synthesize, and a si
Antioxidant properties in a non-polar environment of difluoromethyl bioisosteres of methyl hydroxycinnamates
Martínez, Mario D.,Luna, Lorena,Tesio, Alvaro Y.,Feresin, Gabriela E.,Durán, Fernando J.,Burton, Gerardo
, p. 233 - 244 (2016/02/27)
Objectives Many natural antioxidants have poor pharmacokinetic properties that impair their therapeutic use. For hydroxycinnamic acids (HCAs) and other phenolic antioxidants, their major drawback is their low lipophilicity and a rapid metabolism. The difl
Two-photon fluorescent probes for biological Mg2+ detection based on 7-substituted coumarin
Yin, Haijing,Zhang, Buchang,Yu, Haizhu,Zhu, Lin,Feng, Yan,Zhu, Manzhou,Guo, Qingxiang,Meng, Xiangming
, p. 4306 - 4312 (2015/05/13)
Two novel water-soluble coumarin-based compounds (OC7, NC7) were designed and synthesized as two-photon fluorescent probes for biological Mg2+ detection. The compounds feature a β-keto acid as a high selective binding site for Mg2+ a
Structure-activity relationship study of E6 as a novel necroptosis inducer
Mou, Jianfeng,Park, Ann,Cai, Yu,Yuan, Junying,Yuan, Chengye
supporting information, p. 3057 - 3061 (2015/06/22)
Necroptosis inducers represent a promising potential treatment for drug-resistant cancer. We herein describe the structure modification of E6, which was identified recently as a potent and selective necroptosis inducer. The studies described herein demonstrate for the first time that functionalized biphenyl derivatives possess necroptosis inducer activity. Furthermore, these studies have led to the identification of two promising compounds (5h and 5j) that can be used for further optimization studies as well as mechanism of action investigations.
Synthesis of luminescent ethynyl-extended regioisomers of borate complexes based on 2-(2′-hydroxyphenyl)benzoxazole
Massue, Julien,Frath, Denis,Retailleau, Pascal,Ulrich, Gilles,Ziessel, Raymond
supporting information, p. 5375 - 5386 (2013/05/21)
A series of thirteen luminescent tetrahedral borate complexes based on the 2-(2′-hydroxyphenyl)benzoxazole (HBO) core is presented. Their synthesis includes the incorporation of an ethynyl fragment by Sonogashira cross-coupling reaction, with the goal of
