168908-06-3

Upstream product

• 163332-58-9 (3-Methoxy-cyclopent-1-enesulfonyl)-benzene 

Downstream Products

• 88841-85-4 3-(Phenylseleno)-2-cyclopenten-1-one 
• 81770-99-2 3-(α-hydroxybenzyl)-2-cyclopenten-1-one 
• 67100-39-4 3-benzyl-2-cyclopenten-1-one 
• 168908-04-1 4-Methyl-N-[2-(3-oxo-cyclopent-1-enyl)-ethyl]-benzenesulfonamide 

Relevant academic research and scientific papers

Phosphazene base P2-Et mediated isomerization of vinyl sulfones to allyl sulfones

Treatment of vinyl sulfones with 0.1-0.2 eq of Phosphazene base, P2-Et in THF at 25°C affords the corresponding allyl sulfones in high yield. P2-Et has shown clear superiority to both DBU and KO-t-Bu in these reactions.

Synthesis of beta-substituted cyclopentenones via carbon alkylation of metalated gamma-methoxycyclopentenyl phenylsulfonyl anion

Metalation of γ-methoxyallyl sulfone 13 provides phenylsulfonyl anion 2a which undergoes alkylation followed by hydrolysis to afford β-substituted cyclopentenones.