168969-77-5

Basic information

• Product Name: [(3aS,5S,6aS)-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl]methoxy-tert-butyl-diphenyl-silane
• Synonyms: [(3aS,5S,6aS)-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl]methoxy-tert-butyl-diphenyl-silane
• CAS NO: 168969-77-5
• Molecular Weight: 412.601
• Mol File: 168969-77-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: [(3aS,5S,6aS)-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl]methoxy-tert-butyl-diphenyl-silane(CAS DataBase Reference)
• NIST Chemistry Reference: [(3aS,5S,6aS)-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl]methoxy-tert-butyl-diphenyl-silane(168969-77-5)
• EPA Substance Registry System: [(3aS,5S,6aS)-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl]methoxy-tert-butyl-diphenyl-silane(168969-77-5)

Safety Data

• Hazardous Substances Data: 168969-77-5(Hazardous Substances Data)

Upstream product

• 608-45-7 α-D-arabinopyranose 
• 133074-84-7 Trifluoro-methanesulfonic acid (3aS,5R,6S,6aS)-5-(tert-butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester 
• 133048-89-2 5-O-tert-butyldiphenylsilyl-1,2-O-isopropylidene-β-D-lyxofuranose 
• 172751-32-5 5-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-β-D-threo-pentofuranose-3-ulose 
• 28697-53-2 D-arabinopyranose 
• 1220093-26-4 5-O-t-butyldiphenylsilyl-3-O-(imidazolylthiocarbonyl)-1,2-O-isopropylidene-β-D-threo-pentofuranose 
• 168608-39-7 (3S,4S,5R)-5-(((tert-butyldiphenylsilyl)oxy)methyl)tetrahydrofuran-2,3,4-triol 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 114738-04-4 (3aS,5R,6R,6aS)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol 

Downstream Products

• 1395498-27-7 3-deoxy-1,2-O-isopropylidene-5-O-p-toluenesulfonyl-β-D-threo-pentofuranose 
• 22248-92-6 [(3aS,5S,6aS)-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl]methyl benzoate 

Relevant articles and documents

NOVEL 3-SUBSTITUTED 5-AMINO-6H-THIAZOLO[4,5-D]PYRIMIDINE-2,7-DIONE COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF VIRUS INFECTION

The present invention relates to compounds of formula (I), wherein R1, R2 and R3 are as described herein, and their prodrugs or pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.

Synthesis of 3-Deoxy-d-threopentofuranose 5-phosphate, a substrate of arabinose 5-phosphate isomerase

3-Deoxy-d-threopentofuranose 5-phosphate, a substrate of arabinose 5-phosphate isomerase, has been synthesised starting from d-arabinose. Selective protection of the hydroxyl groups at C-1, C-2, and C-5 allowed deoxygenation of position 3 by conversion into a thiocarbamate and radical reduction. Deprotection and phosphorylation of the primary hydroxyl group and final deprotection of the other hydroxyl groups afforded the desired compound.