168971-54-8

Usage

Uses

Used in Pharmaceutical Industry:
2-(PhenoxyMethyl)Benzonitrile 97 is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs and improve existing ones. Its high purity ensures the quality and efficacy of the final products.
Used in Agrochemical Industry:
In the agrochemical sector, 2-(PhenoxyMethyl)Benzonitrile 97 is utilized as an intermediate in the production of agrochemicals, such as pesticides and herbicides. Its role in these applications is to enhance the effectiveness of these chemicals in protecting crops and managing pests.
Used in Research Applications:
2-(PhenoxyMethyl)Benzonitrile 97 is also employed in research settings for the exploration of new chemical reactions and the development of novel compounds. Its high purity and versatility make it an essential tool for scientific investigations and the advancement of chemical knowledge.

InChI:InChI=1/C14H11NO/c15-10-12-6-4-5-7-13(12)11-16-14-8-2-1-3-9-14/h1-9H,11H2

Upstream product

• 612-13-5 2-cyanobenzyl chloride 
• 108-95-2 phenol 
• 7468-67-9 o-formylbenzonitrile 
• 22115-41-9 2-(bromomethyl)benzonitrile 

Downstream Products

• 168971-56-0 2-phenoxymethyl-benzylamine 

Relevant academic research and scientific papers

Preparation method of benzyl aryl ether and application of benzyl aryl ether in synthesis

and, 6-dihydrodibenzo [11 - b] oxazepine e -11 - ketone compounds are synthesized through a one-step reaction of benzaldehyde compounds and phenolic compounds through one-step reaction. The benzyl aryl ether and 6 and 11 -dihydrodibenzo [b, e] oxazepine -11 - ketone compound respectively have a chemical structure formula shown in a formula I and II. The invention discloses a synthesis method of the compound. Benzaldehyde compound After completion of the reaction, I, 6-dihydrodibenzo [11 - b] oxazepine e ketone compound -11 - can be synthesized through an oxidation or hydrolysis step and a ring closing step after the reaction is complete II.

Combined Cyanoborylation, C-H Activation Strategy for Styrene Functionalization

A one-pot multicomponent copper-catalyzed protocol for borylation/ortho-cyanation of styrene derivatives followed by a Suzuki-Miyaura coupling provides a platform to explore the factors that control the selectivity between distal or proximal functionalization of arenes. The development of divergent nitrile-directed C-H functionalization (acetoxylation, pivalation, and methoxylation) offers an effective approach to rapidly increase synthetic complexity. Finally, the development of a mild reductive decyanation allows a traceless method to access functionalized biaryl motifs.

Synthesis of 2-aryloxymethylbenzonitriles from 2-cyanobenzyl chloride

Fourteen 2-Aryloxymethylbenzonitriles were synthesized from 2-cyanobenzyl chloride and various substituted phenols with potassium carbonate as a base in N,N-dimethyl formamide at 80-110 °C in good to excellent yields. The products, 13 of which are new, we