16915-79-0

Basic information

• Product Name: MEQUINDOX [2-ACETYL-3-METHYLQUINOXALINEDIUM-1,4-DIOLATE]
• Synonyms: MEQUINDOX [2-ACETYL-3-METHYLQUINOXALINEDIUM-1,4-DIOLATE];Mequidox;2-Hydroxymethyl-3-methylquinoxaline 1,4-dioxide;3-Methyl-2-(hydroxymethyl)quinoxaline 1,4-dioxide;GS-7443
• CAS NO: 16915-79-0
• Molecular Formula: C₁₀H₁₀N₂O₃
• Molecular Weight: 206.2
• EINECS: 209-686-8
• Mol File: 16915-79-0.mol
• Article Data: 3

Chemical Properties

• Melting Point: 182-184 °C
• Boiling Point: 491.4±55.0 °C(Predicted)
• Appearance: /
• Density: 1.38±0.1 g/cm3(Predicted)
• PKA: 11.35±0.10(Predicted)
• CAS DataBase Reference: MEQUINDOX [2-ACETYL-3-METHYLQUINOXALINEDIUM-1,4-DIOLATE](CAS DataBase Reference)
• NIST Chemistry Reference: MEQUINDOX [2-ACETYL-3-METHYLQUINOXALINEDIUM-1,4-DIOLATE](16915-79-0)
• EPA Substance Registry System: MEQUINDOX [2-ACETYL-3-METHYLQUINOXALINEDIUM-1,4-DIOLATE](16915-79-0)

Safety Data

• Hazardous Substances Data: 16915-79-0(Hazardous Substances Data)

Usage

Uses

Antibacterial.

InChI:InChI=1/C10H10N2O3/c1-7-10(6-13)12(15)9-5-3-2-4-8(9)11(7)14/h2-5,13H,6H2,1H3

Upstream product

• 10103-90-9 2-acetoxymethyl-3-methyl-quinoxaline 1,4-dioxide 
• 3885-38-9 2-methyl-3-ethoxycarbonylquinoxaline 
• 75620-10-9 2-acetoxymethyl-3-methyl-quinoxaline 
• 25519-55-5 3-methylquinoxaline-2-carbaldehyde 
• 7044-17-9 <2-hydroxymethyl-3-methylquinoxaline> 
• 2379-55-7 2,3-dimethylquinoxaline 

Relevant articles and documents

3 Substituted 2 formylquinoxaline 1,4 dioxides

The methylnitrone of 3 methyl 1,4 dioxidoquinoxaline 2 carboxaldehyde (1) has shown exceptional antibacterial activity in vivo. Derivatives of 3 hydroxymethyl 1,4 dioxidoquinoxaline 2 carboxaldehyde and 3 acetoxymethyl 1,4 dioxidoquinoxaline 2 carboxaldehyde were prepared. Several of these compounds were found to be antibacterial agents of the same order of activity as 1.

Quinoxaline derivatives

The synthesis of quinoxaline and benzimidazole-N-oxides and of ester and amide derivatives of 3-hydroxy-2-quinoxalinecarboxylic acid by a novel process consisting of the reaction between a benzofuroxan and an activated methylene-containing compound under basic conditions.