169191-14-4Relevant academic research and scientific papers
Synthesis, conformational analysis, and biological activity of a rigid carbocyclic analogue of 2'-deoxy aristeromycin built on a bicyclo[3.1.0]hexane template
Siddiqui,Ford Jr.,George,Marquez
, p. 235 - 250 (1996)
A new chiral synthesis of the pseudosugar synthon (1R,2S,4R,5S)-1-[(benzyloxy)methyl]-2-tert-butyloxy-4-hydroxybicyclo[3 .1.0]hexane (12) is reported. This compound was used as a template for the construction of carbocyclic nucleoside 4, a conformationall
Conformationally locked nucleoside analogues
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, (2008/06/13)
Conformationally locked 4',6'-cyclopropane-fused carbocyclic nucleoside analogues. The compounds are prepared by condensing a cyclopropane-fused carbocyclic allylic alcohol with substituted purine or pyrimidine bases. The condensation products are then mo
