89291-76-9

Usage

Uses

Used in Pharmaceutical Industry:
CDX-085 is used as a synthetic intermediate for the production of pharmaceuticals. Its unique chemical structure allows it to be a key component in the synthesis of various drugs, contributing to the development of new medications.
Used in Agrochemical Industry:
In the agrochemical industry, CDX-085 is utilized as a synthetic intermediate for the production of agrochemicals. Its properties make it suitable for the creation of compounds that can be used in agriculture to protect crops and enhance yields.
Used in Chemical Research and Development:
CDX-085 is also used in research and development applications within the chemical industry. Its unique structure and properties make it a valuable compound for exploring new chemical reactions and syntheses, potentially leading to the discovery of novel organic compounds with various applications.
Used in Medicinal Chemistry and Drug Discovery:
Due to its potential biological activities and pharmacological properties, CDX-085 is a subject of interest in medicinal chemistry and drug discovery. Researchers may investigate its interactions with biological targets and evaluate its efficacy in treating specific diseases or conditions, potentially leading to the development of new therapeutic agents.

Upstream product

• 30725-00-9 2,3-O-isopropylidene-D-ribonic-γ-lactone 
• 89291-74-7 (3R,4R)-(-)-6-O-benzyl-1-deoxy-1-(dimethylphosphono)-3,4-O-isopropylidene-D-erythro-2,5-hexodiulose 
• 89291-71-4 (3R,4R)-(-)-6-O-benzyl-1-deoxy-1-(dimethylphosphono)-3,4-O-isopropylidene-D-ribo-hexulose 
• 117251-95-3 (-)-6-O-benzyl-1-deoxy-1-(dimethylphosphono)-3,4-O-isopropylidene-D-ribo-hexofuranose 
• 85846-80-6 5-O-benzyl-2,3-O-isopropylidene-D-ribono-1,4-lactone 
• 66222-28-4 (benzyloxymethyl)tributylstannane 
• 117251-95-3 Dimethyl (6-O-benzyl-3,4-O-isopropylidene-α-D-ribo-2-hexulofuranosyl)phosphonate 
• 89291-75-8 (3aR*,6aR*)-6-Benzyloxymethyl-2,2-dimethyl-4,6a-dihydro-3aH-cyclopenta[d][1,3]dioxol-4-one 
• 89291-72-5 C₃₂H₃₅O₁₀P 
• 89291-71-4 {2-[(4S,5R)-5-((R)-2-Benzyloxy-1-hydroxy-ethyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-2-oxo-ethyl}-phosphonic acid dimethyl ester 
• 89291-74-7 {2-[(4S,5S)-5-(2-Benzyloxy-acetyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-2-oxo-ethyl}-phosphonic acid dimethyl ester 
• 114933-42-5 Acetic acid (3aS,4S,6aS)-4-benzyloxymethyl-2,2-dimethyl-4,6a-dihydro-3aH-cyclopenta[1,3]dioxol-4-yl ester 
• 114948-34-4 (3aS,4S,6aS)-4-Benzyloxymethyl-2,2-dimethyl-4,6a-dihydro-3aH-cyclopenta[1,3]dioxol-4-ol 
• 104010-72-2 (3aS,6aS)-2,2-dimethyl-3a,6a-dihydro-4H-cyclopenta[d][1,3]dioxol-4-one 

Downstream Products

• 156126-13-5 (1aR,1bR,4aS,5S,5aS)-1a-Benzyloxymethyl-3,3-dimethyl-hexahydro-2,4-dioxa-cyclopropa[a]pentalen-5-ol 
• 89291-77-0 (1S,4R,5S)-(-)-3-<(benzyloxy)methyl>-4,5-O-isopropylidene-2-cyclopenten-1-ol methanesulfonate 
• 158631-97-1 (3aS,3bS,6aR,7R,7aS)-7-Benzyloxymethyl-7-iodo-6-(4-methoxy-benzyl)-2,2-dimethyl-hexahydro-1,3,4-trioxa-6-aza-cyclopenta[a]pentalen-5-one 
• 169191-14-4 (1S,4R,5S)-3-<(benzyloxy)methyl>-4-tert-butyloxy-5-hydroxy-2-cyclopenten-1-ol 
• 243462-53-5 (4aS)-4,4a-Anhydro-5-O-benzyl-4a-carba-1-O-(triisopropylsilyl)-2,3-O-isopropylidene-β-L-lyxofuranose 
• 243462-55-7 (4aR)-4,4a-Anhydro-5-O-benzyl-4a-carba-1-O-(triisopropylsilyl)-2,3-O-isopropylidene-β-D-ribofuranose 
• 90597-20-9 1-<(1R,2S,3R)-2,3-dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl>-2,4-(1H,3H)-pyrimidinedione 
• 92642-69-8 (1R,4R,5S)-(-)-1-<3-<(benzyloxy)methyl>-4,5-(isopropylidenedioxy)-2-cyclopentenyl>uracil 
• 246137-20-2 (3aR,4S,6aR)-6-(Benzyloxymethyl)-4-(triisopropylsilyloxy)-2,2-dimethyl-4,6a-dihydro-3aH-cyclopenta[d][1,3]dioxol 
• 100806-47-1 (1S,4R,5S)-(-)-3-<(benzyloxy)methyl>-4,5-O-isopropylidene-2-cyclopenten-1-ol p-toluenesulfonate 
• 290823-01-7 (1S,2S,3S,4S,5S)-(-)-4-(6-amino-purin-9-yl)-1-benzyloxymethyl-6-oxa-bicyclo[3.1.0]hexane-2,3-diol 
• 290823-00-6 (1R,2S,3S,4S,5R)-(-)-4-(6-amino-purin-9-yl)-1-benzyloxymethyl-6-oxa-bicyclo[3.1.0]hexane-2,3-diol 
• 290822-99-0 (1S,2S,3S,4S,5S)-(-)-1-benzyloxymethyl-4-(6-chloropurin-9-yl)-6-oxa-bicyclo[3.1.0]hexane-2,3-diol 
• 290822-98-9 (1R,2S,3S,4S,5R)-(-)-1-benzyloxymethyl-4-(6-chloropurin-9-yl)-6-oxa-bicyclo[3.1.0]hexane-2,3-diol 

Relevant academic research and scientific papers

Design, synthesis, and biological evaluation of fluoroneplanocin A as the novel mechanism-based inhibitor of S-adenosylhomocysteine hydrolase

Fluoroneplanocin A (12) was designed as a novel mechanism-based inhibitor of S-adenosylhomocysteine hydrolase (SAH) and efficiently synthesized via an electrophilic vinyl fluorination reaction (n-BuLi, N-fluorobenzenesulfonimide at -78 °C). Fluoroneplanoc

First synthesis of (-)-neplanocin C

(-)-Neplanocin C (4), a minor component of the neplanocin family of antibiotics and a lead drug for the design of several conformationally constrained nucleosides analogues, was enantioselectively synthesized starting from D-ribono-1,4-lactone via a convergent approach in twelve steps. The proton NMR spectrum of 4 was in agreement with the corresponding natural product. Calculated coupling constants obtained from ab initio molecular modeling studies and from previously published X-ray structure of neplanocin C also corresponded to the spectroscopic data. (C) 2000 Elsevier Science Ltd.

Chiral pool synthesis of 4a-substituted carbocyclic cyclopentanoid nucleoside precursors, I

A suitable protected D-ribono-1,4-lactone derivative has been used for the straightforward chiral pool synthesis of cyclopentanoid nucleoside precursors. Thus, epoxidation followed by deoxygenation or regioselective ring opening led to nucleoside precurso

Synthesis and anti-HIV activity of carbocyclic ring-enlarged 4′,1′a-methano oxetanocin analogues

Synthesis of carbocyclic ring-enlarged 4′,1′a-methano oxetanocin analogues via completely regioselective opening of cyclic sulfites by sodium azide or purine bases is described. Copyright

TOTAL SYNTHESIS OF (+/-)-NEPLANOCIN F

(+/-)-Neplanocin F was synthesized in 12 steps from the racemate (3/4), which was available from D-ribonolactone.

Total Synthesis of (-)-Neplanocin A

An efficient synthesis of neplanocin A, which is easily adaptable for the preparation of other cyclopentenyl containing nucleoside isosteres, has been developed.This enantioselective synthesis provides control of two of the three chiral centers of neplano

SYNTHESIS OF THE CARBOCYCLIC NUCLEOSIDE (-)-NEPLANOCIN A

(-)-Neplanocin A has been prepared in 14 steps from cyclopentadiene (11percent overall yield).

TOTAL SYNTHESIS OF (-)-NEPLANOCIN A

A total synthesis of (-)-neplanocin A has been accomplished in 15 steps starting from the readily available D-(+)-ribonic acid γ-lactone.