169205-96-3 Usage
General Description
2-(Methylthio)oxazolo[5,4-c]pyridine is a chemical compound with a molecular formula of C7H6N2OS. It is a heterocyclic compound that contains a pyridine ring fused to an oxazole ring. The methylthio group on the oxazole ring adds a sulfur atom to the molecule, giving it unique properties and reactivity. 2-(METHYLTHIO)OXAZOLO[5,4-C]PYRIDINE has been studied for its potential biological activities, including its role as a potential antimicrobial and antifungal agent. Additionally, it has been investigated for its potential use as a building block in organic synthesis and medicinal chemistry. Further research is ongoing to explore its potential applications in drug discovery and other fields.
Check Digit Verification of cas no
The CAS Registry Mumber 169205-96-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,9,2,0 and 5 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 169205-96:
(8*1)+(7*6)+(6*9)+(5*2)+(4*0)+(3*5)+(2*9)+(1*6)=153
153 % 10 = 3
So 169205-96-3 is a valid CAS Registry Number.
169205-96-3Relevant articles and documents
Non-imidazole histamine H3 ligands. Part III. New 4-n-propylpiperazines as non-imidazole histamine H3-antagonists
Walczyski, Krzysztof,Zuiderveld, Obbe P.,Timmerman, Henk
, p. 15 - 23 (2007/10/03)
In search for a new lead of non-imidazole histamine H3-receptor antagonists, a series of 1[(2-thiazolopyridine)-4-n-propyl]piperazines, the analogous 1-[(2-oxazolopyridine)-4-npropyl]piperazines, 1-[(2-benzothiazole)-4- n-propyl]piperazine and 1-[(2-benzooxazole)4-n-propyl]piperazine were prepared and in vitro tested as H3-receptor antagonists (the electrically evoked contraction of the guinea-pig jejunum). It appeared that by comparison of homologous pairs the thiazolo derivatives have slightly higher activity than their oxazolo analogues. The most potent compound of these series is the 1-(2-thiazolo[4,5-c]pyridine)-4-n-propylpiperazine (3c) with pA2 = 7.25 (its oxazole analogue (4g) showed pA2 = 6.9). The structure-activity relationships for compounds with various positions of the nitrogen in the benzene ring for the thiazoles compared with oxazoles are discussed.
