169247-38-5

Usage

Chemical structure

Benzene derivative with a bromine atom, an isopropyl group, and a benzyloxy substituent

Functional groups

Bromine atom, isopropyl group, benzyloxy substituent

Applications

Organic synthesis, chemical research, pharmaceuticals, agrochemicals, specialty chemicals

Reactivity

Suitable for various applications due to its chemical structure

Utilization

Building block in the synthesis of more complex organic compounds

Importance

Versatile chemical in the field of organic chemistry

Upstream product

• 26307-50-6 4-bromo-2-isopropyl-phenol 
• 100-39-0 benzyl bromide 
• 100-44-7 benzyl chloride 
• 88-69-7 2-(1-methylethyl)phenol 

Downstream Products

• 373642-03-6 4-benzyloxy-3-isopropylbenzaldehyde 
• 211110-63-3 sobetirome 
• 1000606-05-2 1-benzyloxy-4-chloromethyl-2-isopropylbenzene 
• 1000603-95-1 (4-benzyloxy-3-isopropylphenyl)methanol 
• 904925-69-5 [4-(4-isobutyl-3-isopropyl-benzyl)-3,5-dimethyl-phenoxy]-triisopropyl-silane 
• 904925-64-0 4-(2,6-dimethyl-4-triisopropylsilanyloxy-benzyl)-2-isopropyl-phenol 
• 904925-68-4 [4-(3,4-diisopropyl-benzyl)-3,5-dimethyl-phenoxy]-triisopropyl-silane 
• 904925-66-2 [4-(4-ethyl-3-isopropyl-benzyl)-3,5-dimethyl-phenoxy]-triisopropyl-silane 
• 904925-79-7 [4-(3-isopropyl-4-propyl-benzyl)-3,5-dimethyl-phenoxy]-acetic acid ethyl ester 
• 904925-81-1 [4-(4-isobutyl-3-isopropyl-benzyl)-3,5-dimethyl-phenoxy]-acetic acid ethyl ester 
• 904925-80-0 [4-(3,4-diisopropyl-benzyl)-3,5-dimethyl-phenoxy]-acetic acid ethyl ester 
• 904925-78-6 [4-(4-ethyl-3-isopropyl-benzyl)-3,5-dimethyl-phenoxy]-acetic acid ethyl ester 
• 904925-77-5 4-(4-isobutyl-3-isopropyl-benzyl)-3,5-dimethyl-phenol 
• 904925-75-3 4-(3-isopropyl-4-propyl-benzyl)-3,5-dimethyl-phenol 

Relevant academic research and scientific papers

Liver-targeting compound with thyroid hormone receptor stimulating agent characteristics and pharmaceutical composition of liver targeting compound

The invention belongs to the field of biomedicines, particularly relates to the field of targeting drugs and more specifically relates to a liver-targeting compound with thyroid hormone receptor stimulating agent characteristics and a pharmaceutical compo

Synthesis and pharmacological characterization of 1-benzyl-4-aminoindole- based thyroid hormone receptor β agonists

A series of 1-benzylindole-based TRβ agonists were prepared and evaluated. Compounds 11b′ and 11c′ were found to have cholesterol-lowering in a rat model with marginal effects on cardiac function and HPT axis. The present work illustrates the potential use of indoles as inner ring isosteres.

NOVEL 6-5 BICYCIC HETEROCYCLIC DERIVATIVE AND MEDICAL USE THEREOF

An object of the present invention is to provide a medicament as a thyroid hormone receptor ligand which is sufficient in drug efficacy and safety, and has the excellent action as a drug. The present invention provides a compound represented by the following general formula (I) or a pharmaceutically acceptable salt thereof: [wherein [Chemical Formula 2] is a single bond or a double bond; A is -CH2- or -CO-; X, Y, and Z are each independently a nitrogen atom or a carbon atom; R1 is a hydrogen atom or an aralkyl group; R2 is an alkyl group or an aralkyl group, etc.; R3 is a hydrogen atom or an alkyl group, etc.; R4 is a hydrogen atom or an alkyl group; R5 is a hydrogen atom, an alkyl group or a halo lower alkyl group, etc.; R6 is a hydrogen atom or an alkyl group; R7 is a hydrogen atom, etc.; R8 is a hydrogen atom, or an alkyl group, etc.; and E is -NHCO-G-COR12, etc. (wherein G is a single bond or an alkylene group, and R12 is a hydroxy group or an alkoxy group)].

Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound

There is disclosed a dihalopropene compound of the formula I: STR1 wherein l is an integer of 1 to 5; m is an integer of 1 to 4; R1 's and R2 's are the same or different and are independently halogen or various other groups; D is oxygen; X's are the same or different and are independently chlorine or bromine; Y is oxygen; Z, P and Q are the same or different and are independently nitrogen or CH, provided that P and Q are not simultaneously nitrogen, and when Y is sulfur, Z is CH. Also disclosed is an insecticide/acaricide comprising the dihalopropene compound as an active ingredient. The dihalopropene compound exhibits excellent insecticidal/acaricidal action. Further disclosed is an intermediate compound for use in the production of the dihalopropene compound.