904925-66-2

Upstream product

• 904925-63-9 (4-benzyloxy-3-isopropyl-phenyl)-(2,6-dimethyl-4-triisopropylsilanyloxy-phenyl)-methanol 
• 904925-64-0 4-(2,6-dimethyl-4-triisopropylsilanyloxy-benzyl)-2-isopropyl-phenol 
• 169247-38-5 1-benzyloxy-4-bromo-2-isopropylbenzene 
• 904925-65-1 trifluoro-methanesulfonic acid 4-(2,6-dimethyl-4-triisopropylsilanyloxy-benzyl)-2-isopropyl-phenyl ester 
• 925-90-6 ethylmagnesium bromide 

Downstream Products

• 904925-78-6 [4-(4-ethyl-3-isopropyl-benzyl)-3,5-dimethyl-phenoxy]-acetic acid ethyl ester 

Relevant academic research and scientific papers

A functionally orthogonal ligand-receptor pair created by targeting the allosteric mechanism of the thyroid hormone receptor

Nuclear receptors are ligand-dependent transcription factors that are of interest as potential tools to artificially regulate gene expression. Ligand binding induces a conformational change involving helix-12 which forms part of the dimerization interface