169330-83-0Relevant academic research and scientific papers
Kinetic Resolution of Sulfinamides via Asymmetric N-Allylic Alkylation
Zheng, Gao-Liang,Lu, Chenxi,Cheng, Jin-Pei,Li, Xin
, p. 8499 - 8504 (2021/10/25)
An efficient kinetic resolution of sulfinamides via an asymmetric N-allylic alkylation reaction was realized using hydroquinine as a catalyst under mild conditions. The kinetic resolution of a range of Morita-Baylis-Hillman adducts and N-aryl tert-butylsulfinamides was highly effective. In addition, the synthetic utility of the protocol was demonstrated by a scaled-up reaction. Density functional theory calculations provide convincing evidence for the interpretation of stereoselection.
N-phosphino-p-tolylsulfinamide ligands: Synthesis, stability, and application to the intermolecular Pauson-Khand reaction
Reves, Marc,Achard, Thierry,Sola, Jordi,Riera, Antoni,Verdaguer, Xavier
experimental part, p. 7080 - 7087 (2009/05/09)
(Chemical Equation Presented) Here we synthesized a family of racemic and optically pure N-phosphino-p-tolylsulfinamide (PNSO) ligands. Their stability and coordination behavior toward dicobalt-alkyne complexes was evaluated. Selectivities of up to 3:1 we
Synthesis and Reactivity of Enantiomerically Pure N-Acyl N-Alkyl p-Toluenesulfinamides
Garcia-Ruano, Jose L.,Alonso, Raquel,Zarzuelo, Maria M.,Noheda, Pedro
, p. 1133 - 1142 (2007/10/02)
The syntheses of different enantiomerically N-acyl N-alkyl p-toluenesulfinamides 5, by N-sulfinylation of primary amines with (S)-menthyl-p-tolylsulfinate followed by N-acylation of the resulting sulfinamides are reported.Their reactions with some C-nucleophiles take place at the sulfur atom exclusively with complete retension of the enantiomeric purity, revealing their ability as sulfinylating agents.In this sense, their comparison with other reagents popularly used, revealed that 5 have some important advantages.
