169378-52-3

Basic information

• Product Name: 1-BUTYL-1H-IMIDAZOLE-2-CARBALDEHYDE
• Synonyms: 1-BUTYL-1H-IMIDAZOLE-2-CARBALDEHYDE;1-butyl-2-imidazolecarboxaldehyde;1-butylimidazole-2-carbaldehyde
• CAS NO: 169378-52-3
• Molecular Formula: C₈H₁₂N₂O
• Molecular Weight: 152.19
• Mol File: 169378-52-3.mol
• Article Data: 16

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-BUTYL-1H-IMIDAZOLE-2-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BUTYL-1H-IMIDAZOLE-2-CARBALDEHYDE(169378-52-3)
• EPA Substance Registry System: 1-BUTYL-1H-IMIDAZOLE-2-CARBALDEHYDE(169378-52-3)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 169378-52-3(Hazardous Substances Data)

Usage

General Description

1-BUTYL-1H-IMIDAZOLE-2-CARBALDEHYDE is a chemical compound also known as butylimidazole. It is an aldehyde compound with the molecular formula C9H14N2O. It is commonly used as a reagent for organic synthesis and as a starting material for the production of various pharmaceuticals, agrochemicals, and dyes. It is a colorless to pale yellow liquid with a pungent odor and is highly flammable. 1-BUTYL-1H-IMIDAZOLE-2-CARBALDEHYDE is also used in the production of surfactants, which are used in various industrial processes and consumer products. Additionally, it is used as a corrosion inhibitor, an anti-microbial agent, and in the production of plasticizers.

Upstream product

• 4316-42-1 1-Butylimidazole 
• 68-12-2 N,N-dimethyl-formamide 
• 109-65-9 1-bromo-butane 
• 10111-08-7 2-imidazolecarbaldehyde 
• 288-32-4 1H-imidazole 
• 542-69-8 1-iodo-butane 

Downstream Products

• 1260839-08-4 1-n-butylimidazole-2-carboxylic acid 
• 497853-03-9 7-{4-[2-(butoxy)ethoxy]phenyl}-1-isobutyl-N-({4-[(1-butyl-1H-imidazol-2-yl)methyl]sulfanyl}phenyl)-2,3-dihydro-1H-1-benzazepine-4-carboxamide 

Relevant articles and documents

Spin crossover star-shaped metallomesogens of iron(II)

Three new types of spin crossover (SCO) metallomesogens of FeII based on symmetric tripod ligands and their magnetic and structural properties are reported here. These were obtained by condensation of tris(2-aminoethyl)amin (tren) with the aldehyde derived from 3-alkoxy-6-methylpyridine (mpyN, N (number of carbon atoms in n-alkyl chains) = 8, 18), 1-alkyl-1H-imidazole (imN, N = 4, 16, 18, 20, 22), or 1-alkyl-1H-benzimidazole (bimN, N = 6, 14, 16, 18, 20). A complex derived from 1-octadecyl-1H-naphtho[2,3-d]imidazole (nim18) retains the high spin state at any temperature. Single crystals of the short-chain complexes were investigated by a combination of X-ray crystallography, magnetic measurements and Moessbauer spectroscopy. Generally, in comparison with the short-chain complexes the long-chain complexes display more gradual SCO and undergo a phase transition crystal-liquid crystal that is reflected in their magnetic properties. Characterization by X-ray powder diffractometry and differential calorimetry reveal formation of a smectic mesophase upon melting.

Direct and Regioselective Introduction of Acetals into Imidazoles at the 2-Position by an Iridium-Catalyzed Reaction with Formates in the Presence of Hydrosilanes

The iridium-catalyzed reaction of imidazoles with formates in the presence of hydrosilanes as coreactants led to the production of 2-[(alkoxy)(siloxy)methyl]imidazoles. Dimethyl acetylenedicarboxylate was the additive of choice for the reaction in terms of reaction efficiency. No reaction was observed in the absence of the hydrosilanes. Whereas substituents at the 1- and 5-positions on the imidazole ring did not affect the reaction, substituents at the 4-position greatly retarded the reaction. The regioselective reaction of 1-methyl-1,2,4-triazole occurred at the carbon atom between the sp3 and sp2 nitrogen atoms of the ring but not between two sp2 nitrogen atoms. The products were converted into imidazole 2-carbaldehydes by hydrolysis under acidic conditions.

CYCLIC AMINE DERIVATIVE AND PHARMACEUTICAL USE THEREOF

An object of the present invention is to provide a compound exerting an analgesic effect against pain, in particular, neuropathic pain and/or fibromyalgia syndrome. The present invention provides a cyclic amine derivative represented by the following general formula, or a pharmacologically acceptable salt thereof.

Bioinspired nanophotosensitizers: Synthesis and characterization of porphyrin-noble metal nanoparticle conjugates

A methodology to enhance biological delivery of photosensitizers by incorporating them into nanomaterials has been developed. In order to prepare photosensitizer nanoconjugates as biocompatible and selective probes, initially, bioconjugatable porphyrinic