4316-42-1Relevant articles and documents
The effect of ultrasound on the N-alkylation of imidazole over alkaline carbons: Kinetic aspects
Ferrera-Escudero,Perozo-Rondón,Calvino-Casilda,Casal,Martín-Aranda,López-Peinado,Durán-Valle
, p. 26 - 32 (2010)
N-Alkylimidazoles have been synthesized by sonochemical irradiation of imidazole and 1-bromobutane using alkaline-promoted carbons. The catalysts were characterized by X-ray photoelectron spectroscopy, thermal analysis and nitrogen adsorption isotherms. Under the experimental conditions, N-alkylimidazoles can be prepared with a high activity and selectivity. It is observed that imidazole conversion increases in parallel with increasing the basicity of the catalyst. For comparison, the alkylation of imidazole has also been performed in a batch reactor system under thermal activation.
-
King et al.
, p. 1607 (1978)
-
Sonochemical Synthesis and Characterization of Some Alkoxyl-Functionalized Ionic Liquids Derived from 1-Butoxyl-3-butyl Imidazolium Bromide
Ameta, Garima,Punjabi, Pinki B.
, p. 1068 - 1076 (2017)
Non-conventional techniques, such as power ultrasound (US) has been used to promote one-pot synthesis of second generation ionic liquids (ILs), reducing reaction times and improving yields. Because of the emerging importance of the ILs as green materials with wide ranging applications and our general interests in green processes such as sonication, 1-butoxyl-3-butyl imidazolium bromide (alkoxyl-functionalized) and their derivatives were synthesized using a facile and green US assisted procedure. Their structures were characterized by FT–IR, 1H-NMR, 13C-NMR and mass spectroscopy.
Synthesis, Characterization, Thermal Analyses, and Spectroscopic Properties of Novel Naphthyl-Functionalized Imidazolium Ionic Liquids
Yao, Meihuan,Li, Qing,Xia, Yanqiu,Liang, Yongmin
, p. 502 - 507 (2018)
A series of novel ionic liquids based on naphthyl-functionalized imidazolium cation have been prepared. Their structure was characterized by NMR. The thermal stabilities of the prepared liquids were studied by thermal gravimetric analysis. The new ionic liquids containing NTf- 2 anion display significantly higher thermal stabilities (CloseSPigtSPi400°C). Anion exchange to PF- 6, BF- 4, and Br– decreases the thermal stabilities of such ionic liquids. Fluorescence and UV–Vis absorption spectroscopy were used to study the spectroscopic properties of the ionic liquids. Compared with common ionic liquids, the described ionic liquids provide robust fluorescence properties and remarkably increased UV–Vis absorption. This research may enrich the field of functionalized ionic liquids and provide a platform for extension of ionic liquid applications.
Sonochemical synthesis and characterization of imidazolium based ionic liquids: A green pathway
Ameta, Garima,Pathak, Arpit Kumar,Ameta, Chetna,Ameta, Rakshit,Punjabi, Pinki B.
, p. 934 - 937 (2015)
The emerging importance of sonochemistry as "green" process and ionic liquids (ILs) as "green" materials with their wide applications are rapidly increasing. Imidazolium-based ionic liquid derivatives are synthesized using a facile and green ultrasound-assisted procedure. Their structures were characterized by IR, 1H-NMR, 13C-NMR and Mass spectroscopy. The main advantages of the present procedure as compared with conventional method are mainly, its milder conditions, shorter reaction time, higher yields and selectivity without the need for a transition metal or base catalyst.
Mixing divalent ionic liquids: effects of charge and side-chains
Bakis, Eduards,van den Bruinhorst, Adriaan,Pison, Laure,Palazzo, Ivan,Chang, Thomas,Kjellberg, Marianne,Weber, Cameron C.,Costa Gomes, Margarida,Welton, Tom
, p. 4624 - 4635 (2021/03/15)
We have prepared novel divalent ionic liquids (ILs) based on the bis(trifluoromethylsulfonyl)imide anion where two charged imidazolium groups in the cations are either directly bound to each other or linked by a single atom. We assessed the influence of the side-chain functionality and divalency on their physical properties and on the thermodynamics of mixing. The results indicate that shortening the spacer of a divalent IL reduces its thermal stability and increases its viscosity. Mixtures of divalent and monovalent ILs show small but significant deviations from ideality upon mixing. These deviations appear to depend primarily on the (mis)match of the nature and length of the cation side-chain. The non-ideality imposed by mixing ILs with different side-chains appears to be enhanced by the increase in formal charge of the cations in the mixture.
Cell Permeable Imidazole-Desferrioxamine Conjugates: Synthesis and in Vitro Evaluation
Pramanik, Shreya,Chakraborty, Saikat,Sivan, Malavika,Patro, Birija S.,Chatterjee, Sucheta,Goswami, Dibakar
, p. 841 - 852 (2019/03/07)
Desferrioxamine (DFO), a clinically approved iron chelator used for iron overload, is unable to chelate labile plasma iron (LPI) because of its limited cell permeability. Herein, alkyl chain modified imidazolium cations with varied hydrophobicities have been conjugated with DFO. The iron binding abilities and the antioxidant properties of the conjugates were found to be similar to DFO. The degree of cellular internalization was much higher in the octyl-imidazolium-DFO conjugate (IV) compared with DFO, and IV was able to chelate LPI in vitro. This opens up a new avenue in using N-alkyl imidazolium salts as a delivery vector for hydrophilic cell-impermeable drugs.
