16939-00-7Relevant articles and documents
Lithiation of 1-arylimidazol-2(1H)-ones and 1-aryl-4,5-dihydroimidazol- 2(1H)-ones
Llopart, Carme Cantos,Ferrer, Conchita,Joule, John A.
, p. 1649 - 1661 (2007/10/03)
1-Arylimidazol-2(1H)-ones are shown to be readily lithiated, using 2 mol equiv. of n-butyllithium, on the benzene ring, ortho to the heterocycle. 1-Aryl-4,5-dihydroimidazol-2(1H)-ones also undergo metalation on the aromatic substitutuent ortho to the heterocycle, but less efficiently. 1-Aryl-3-methylimidazol-2(1H)-ones are lithiated on the heterocyclic ring and then on the benzene ring ortho to the heterocycle. No ortho-directing effect was found for 1-aryl-4,5-dihydro-3-methylimidazol-2(1H)-ones.
Photochemical decomposition of phenazone derivatives. Part 5: Isolation and identification of decomposition products in aqueous solution
Marciniec
, p. 30 - 33 (2007/10/02)
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