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BOC-ILE-ONP is a chemical compound that integrates the amino acid isoleucine with a BOC (tert-butyloxycarbonyl) protecting group and an ONP (o-nitrophenyl) ester. BOC-ILE-ONP plays a crucial role in peptide synthesis, serving as a fundamental building block for the assembly of larger peptide molecules. The BOC group shields the reactive amine group of isoleucine, preventing unwanted side reactions, while the ONP ester group aids in the coupling process of isoleucine with other amino acids. As a vital reagent in peptide chemistry, BOC-ILE-ONP enables the construction of intricate peptide structures for a wide range of biological and chemical applications.

16948-38-2

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16948-38-2 Usage

Uses

Used in Peptide Synthesis:
BOC-ILE-ONP is used as a building block for the creation of larger peptide molecules. Its inclusion in the synthesis process is crucial for the formation of complex peptide structures that can be utilized in various applications.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, BOC-ILE-ONP is used as a key component in the synthesis of bioactive peptides. These peptides can have therapeutic properties and are used for the treatment of various diseases and conditions.
Used in Research and Development:
BOC-ILE-ONP is utilized in research and development settings to explore the properties and potential applications of newly synthesized peptides. This includes studying their interactions with biological targets and assessing their efficacy and safety.
Used in Chemical Industry:
In the chemical industry, BOC-ILE-ONP may be employed in the synthesis of specialty chemicals and materials that incorporate peptide-based structures, such as peptide-based polymers or peptide-conjugated compounds with specific functions.
Used in Diagnostics:
BOC-ILE-ONP can be used in the development of diagnostic tools that rely on peptide-based assays, where specific peptide sequences are designed to interact with target molecules for detection or measurement purposes.

Check Digit Verification of cas no

The CAS Registry Mumber 16948-38-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,9,4 and 8 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 16948-38:
(7*1)+(6*6)+(5*9)+(4*4)+(3*8)+(2*3)+(1*8)=142
142 % 10 = 2
So 16948-38-2 is a valid CAS Registry Number.
InChI:InChI=1/C17H24N2O6/c1-6-11(2)14(18-16(21)25-17(3,4)5)15(20)24-13-9-7-12(8-10-13)19(22)23/h7-11,14H,6H2,1-5H3,(H,18,21)/t11-,14-/m0/s1

16948-38-2 Well-known Company Product Price

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  • Aldrich

  • (15128)  Boc-Ile-ONp  ≥98.0% (TLC)

  • 16948-38-2

  • 15128-5G

  • 1,014.39CNY

  • Detail

16948-38-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (2S,3S)-4-Nitrophenyl 2-((tert-butoxycarbonyl)amino)-3-methylpentanoate

1.2 Other means of identification

Product number -
Other names (4-nitrophenyl) (2S,3S)-3-methyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:16948-38-2 SDS

16948-38-2Relevant academic research and scientific papers

SULFOXONIUM YLIDE DERIVATIVES AS PROBES FOR CYSTEINE PROTEASE

-

Paragraph 0367; 0374-0376, (2020/07/14)

The present invention relates to compounds of formula I bearing a sulfoxonium ylide moiety as warhead, or salts thereof. Such compounds can be used as activity-based probes for cysteine proteases such as cathepsin X, in methods of detecting cysteine protease activity and in related diagnostic or therapeutic methods.

Oxo-ester mediated native chemical ligation: Concept and applications

Wan, Qian,Chen, Jin,Yuan, Yu,Danishefskr, Samuel J.

supporting information; scheme or table, p. 15814 - 15816 (2009/05/16)

A direct oxo-ester peptide ligation method has been developed. Through the use of an activated C-terminal para nitrophenyl ester (1), it is possible to achieve direct cysteine ligations (1 + 2 → 4). Peptide substrates incorporating bulky C-terminal amino acids (1) can be accommodated with high reaction efficiency. Copyright

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