169529-25-3Relevant academic research and scientific papers
Adenosine Kinase Inhibitors. 3. Synthesis, SAR, and Antiinflammatory Activity of a Series of L-Lyxofuranosyl Nucleosides
Ugarkar, Bheemarao G.,Castellino, Angelo J.,DaRe, Jay S.,Ramirez-Weinhouse, Michele,Kopcho, Joseph J.,Rosengren, Sanna,Erion, Mark D.
, p. 4750 - 4760 (2007/10/03)
Chronic inflammatory diseases, such as arthritis and rheumatoid arthritis, remain major health problems worldwide. We previously demonstrated that adenosine kinase inhibitors (AKIs) exhibit antiinflammatory effects by inhibiting TNF-α production, neutroph
4'-Thio-β-D-oligoribonucleotides: Nuclease resistance and hydrogen bonding properties
Leydier,Bellon,Barascut,Imbach
, p. 1027 - 1030 (2007/10/02)
The syntheses and the study of nuclease resistance and hydrogen bonding of modified oligoribonucleotides, i.e. 4'-thio-β-D-oligoribonucleotides (4'-S-RNA), are reported.
