16965-06-3

Basic information

• Product Name: BOC-LYS(TFA)-OH
• Synonyms: BOC-L-LYS(TFA)-OH;BOC-LYS(TFA)-OH;BOC-LYSINE(TFA)-OH;BOC-N-EPSILON-TRIFLUOROACETYL-L-LYSINE;BOC-N-EPSILON-TFA-L-LYSINE;N-ALPHA-BOC-N-EPSILON-TRIFLUOROACETYL-L-LYSINE;N-ALPHA-T-BUTYLOXYCARBONYL-N-EPSILON-TRIFLUORACETYL-L-LYSINE;N-ALPHA-T-BUTOXYCARBONYL-N-EPSILON-TRIFLUOROACETYL-L-LYSINE
• CAS NO: 16965-06-3
• Molecular Formula: C₁₃H₂₁F₃N₂O₅
• Molecular Weight: 342.31
• Product Categories: AMINOACIDS DERIVATIVES;Amino Acids
• Mol File: 16965-06-3.mol
• Article Data: 5

Chemical Properties

• Melting Point: 102-105 °C
• Boiling Point: 485.585 °C at 760 mmHg
• Flash Point: 247.473 °C
• Appearance: White/Powder
• Density: 1.255 g/cm³
• Vapor Pressure: 9.25E-11mmHg at 25°C
• Refractive Index: 1.449
• Storage Temp.: -15°C
• Solubility: Soluble in DMSO.
• PKA: 3.97±0.21(Predicted)
• CAS DataBase Reference: BOC-LYS(TFA)-OH(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-LYS(TFA)-OH(16965-06-3)
• EPA Substance Registry System: BOC-LYS(TFA)-OH(16965-06-3)

Safety Data

• WGK Germany: 3
• F: 10-21
• HazardClass: IRRITANT
• Hazardous Substances Data: 16965-06-3(Hazardous Substances Data)

Usage

Chemical Properties

White powder

Uses

Boc-Lys(Tfa)-OH (cas# 16965-06-3) is a compound useful in organic synthesis.

InChI:InChI=1/C13H21F3N2O5/c1-12(2,3)23-11(22)18-8(9(19)20)6-4-5-7-17-10(21)13(14,15)16/h8H,4-7H2,1-3H3,(H,17,21)(H,18,22)(H,19,20)/t8-/m0/s1

Upstream product

• 383-63-1 ethyl trifluoroacetate, 
• 13734-28-6 Boc-Lys-OH 
• 24424-99-5 di-tert-butyl dicarbonate 
• 10009-20-8 (S)-6-trifluoroacetylamino-2-aminohexanoic acid 
• 84624-27-1 Boc-Lys(Fmoc)-OH 
• 383-64-2 S-ethyl trifluoroacetate 

Downstream Products

• 142846-53-5 Boc-Lys(COCF₃)-Gly-OCH₂Ph 
• 34695-46-0 N-alpha-BOC-N-epsilon-TFA-lysine succinimidyl ester 
• 1375701-67-9 α-N-Boc-ε-N-trifluoroacetyl-lysine-CBT 
• 1242276-50-1 C₂₇H₃₇F₃N₄O₅ 
• 77829-75-5 C₂₀H₂₈F₃N₃O₅ 
• 142824-66-6 Boc-Lys(COCF₃)-Lys(COCF₃)-Gly-OCH₂Ph 

Relevant articles and documents

Synthesis of a radioiodinated park nucleotide analog: A new tool for antibacterial screen development

The Park nucleotide is an important biological building block used in the construction of bacterial cell walls. Herein, we describe the synthesis of a radiolabeled Park nucleotide analog, p-iodophenoxyacyl-Ala-(D)-iso- GluLys-(D)-Ala-(D)-Ala-OH-[125

Control of lysyl oxidase activity through site-specific deuteration of lysine

Lysyl oxidase (LOX) is implicated in several extracellular matrix related disorders, including fibrosis and cancer. Methods of inhibition of LOX in vivo include antibodies, copper sequestration and toxic small molecules such as β-aminopropionitrile. Here,

Reversible protection of lysine to facilitate the purification of protected peptide segments

The polarity of temporarily free lysine side chains can be exploited to aid in the purification of protected peptides. The amine groups can easily be reprotected after the purification step. Impurities in commercial TFE1 can cause trifluoroacetylation of free primary amines.