169673-44-3Relevant academic research and scientific papers
L-tryptophan urea amides as NK1/NK2 Dual antagonists
Qi, Hongbo,Shah, Shrenik K.,Cascieri, Margaret A.,Sadowski, Sharon J.,MaCcoss, Malcolm
, p. 2259 - 2262 (1998)
We report that a systematic modification of an NK1 receptor selective antagonist resulted in the identification of novel compounds, 4c and 4d, with high affinity for both NK1 and NK2 receptors.
TRYPTHOPHAN UREAS AS NEUROKINNIN ANTAGONISTS
-
, (2008/06/13)
Disclosed are Substituted azacycles of formula I STR1 are tachykinin receptor antagonists useful in the treatment of inflammatory diseases, pain or migraine, and asthma. In particular compounds of formula I are shown to be neurokinin antagonists.
