L-tryptophan urea amides as NK1/NK2 Dual antagonists

DOI: 10.1016/S0960-894X(98)00395-3

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2259 - 2262 (1998)

Update date:2022-07-31

Topics:

Authors:

Qi, Hongbo

Shah, Shrenik K.

Cascieri, Margaret A.

Sadowski, Sharon J.

MaCcoss, Malcolm

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Article abstract of DOI:10.1016/S0960-894X(98)00395-3

We report that a systematic modification of an NK₁ receptor selective antagonist resulted in the identification of novel compounds, 4c and 4d, with high affinity for both NK₁ and NK₂ receptors.

Full text of DOI:10.1016/S0960-894X(98)00395-3

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