169736-20-3

Upstream product

• 187590-77-8 1,4-anhydro-2,3,5-tri-O-benzyl-4-thio-D-arabinitol 
• 160882-25-7 3-O-benzyl-1-deoxy-4-thio-D-arabino-furanose 
• 100-44-7 benzyl chloride 
• 1600-27-7 mercury(II) diacetate 
• 169736-19-0 benzyl 2,3,5-tri-O-benzyl-4-deoxy-4-thio-D-thioarabinofuranoside 

Downstream Products

• 191794-47-5 1-((3S,4S,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-thiophen-2-yl)-5-iodo-1H-pyrimidine-2,4-dione 
• 191794-49-7 1-((3S,4S,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-thiophen-2-yl)-5-((E)-2-bromo-vinyl)-1H-pyrimidine-2,4-dione 
• 191794-48-6 1-((3S,4S,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-thiophen-2-yl)-5-((E)-2-chloro-vinyl)-1H-pyrimidine-2,4-dione 
• 191794-52-2 7-((3S,4S,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-thiophen-2-yl)-7H-purin-6-ylamine 
• 191794-50-0 9-((3S,4S,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-thiophen-2-yl)-9H-purin-6-ylamine 
• 191794-46-4 1-((3S,4S,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-thiophen-2-yl)-5-methyl-1H-pyrimidine-2,4-dione 
• 191794-45-3 1-((3S,4S,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-thiophen-2-yl)-5-ethyl-1H-pyrimidine-2,4-dione 
• 169514-88-9 9-(2,3,5-tri-O-benzyl-4-thio-β-D-arabinofuranosyl)-2,6-dichloropurine 
• 169514-87-8 9-(2,3,5-tri-O-benzyl-4-thio-α-D-arabinofuranosyl)-2,6-dichloropurine 
• 15023-77-5 1-(6-amino-purin-9-yl)-β-D-4-thio-1-deoxy-arabinofuranose 
• 6741-71-5 5-methyl-1-(4-thio-α-D-arabinofuranosyl)uracil 
• 4303-00-8 (2S,3S,4S,5R)-2-(6-Amino-purin-9-yl)-5-hydroxymethyl-tetrahydro-thiophene-3,4-diol 
• 26527-36-6 5-methyl-1-(β-D-4-thio-arabinofuranosyl)-1H-pyrimidine-2,4-dione 
• 1055036-45-7 C₅₂H₅₄O₇S₂ 

Relevant academic research and scientific papers

Preparation of thioarabinofuranosyl compounds and use thereof

Patients suffering from cancer are treated by being administered a compound represented by the following formula: wherein each R individually is H or an aliphatic or aromatic acyl group; A is selected from the group consisting of wherein X is selected from the group consisting of hydrogen, fluorine, alkoxy, alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, amino, monoalkylamino, dialkylamino, cyano and nitro. The above compounds also inhibit DNA replication in mammalian cells,

Purine 4'-thioarabinonucleosides

The present invention provides a novel purine 4'-thioarabinonucleoside represented by the following formula ?1!: STR1 wherein B represents a purine base other than adenine. Also disclosed are a method for preparing the purine 4'-thioarabinonucleoside and pharmaceutical compositions containing the purine 4'-thioarabinonucleoside.

A facile, alternative synthesis of 4'-thioarabinonucleosides and their biological activities

4'-Thioarabinonucleosides, which are potential antiviral agents, were synthesized from D-glucose. 1,4-Anhydro-4-thioarabitol (8), which can be derived from diacetone glucose in nine steps, was subjected to Pummerer rearrangement after protection of the hy

The synthesis and biological activity of certain 4'-thionucleosides

Results are presented on the synthesis and biological activity of several types of 4'-thionucleosides as potential anticancer agents. Detailed studies on the mechanism of action of 4'-thiothymidine are also presented.