160882-25-7Relevant articles and documents
Gram-level total synthesis method of sulfur onium salt type natural product neoponkoranol extracted from salacia plants
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, (2019/02/19)
The invention belongs to the field of chemical synthesis and particularly relates to a gram-level total synthesis method of a sulfur onium salt type natural product neoponkoranol with hypoglycemic activity extracted from salacia plants. According to the m
2'-deoxy-2'-(substituted or unsubstituted)methylidene-4'-thionucleosides
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, (2008/06/13)
The present invention relates to 2'-deoxy-2'-(substituted or unsubstituted)methylidene-4'-thionucleosides having excellent antitumor activity, represented by formula ?I!: STR1 wherein B represents a pyrimidine or purine base, R1 and R2, which may be the same or different, represent hydrogen, a cyano group or alkyl group, and R3 represents hydrogen or a phosphoric acid residue, and a method for producing the same, and a use of the same.
Synthesis and biological activities of 2'-modified 4'-thionucleosides
Yoshimura, Yuichi,Kitano, Kenji,Watanabe, Mikari,Satoh, Hiroshi,Sakata, Shinji,Miura, Shinji,Ashida, Noriyuki,Machida, Haruhiko,Matsuda, Akira
, p. 1103 - 1106 (2007/10/03)
We have synthesized 4'-thioDMDC, 4'-thiogemcitabine, and 4'- thioarabinonucleosides, as potential antitumor and antiviral agents, originated from D-glucose. Biological activities of these compounds are also described.