169736-19-0Relevant academic research and scientific papers
Synthesis and biological activity of certain 4'-thio-D- arabinofuranosylpurine nucleosides
Secrist III, John A.,Tiwari, Kamal N.,Shortnacy-Fowler, Anita T.,Messini, Lea,Riordan, James M.,Montgomery, John A.,Meyers, Scott C.,Ealick, Steven E.
, p. 3865 - 3871 (2007/10/03)
A series of 4'-thio-D-arabinofuranosylpurine nucleosides was prepared and evaluated as potential anticancer agents. The details of a convenient and high-yielding synthesis of the carbohydrate precursor 1-O-acetyl-2,3,5-tri- O-benzyl-4-thio-D-arabinofurano
The synthesis and biological activity of certain 4'-thionucleosides
Secrist III,Parker,Tiwari,Messini,Shaddix,Rose,Bennett Jr.,Montgomery
, p. 675 - 686 (2007/10/02)
Results are presented on the synthesis and biological activity of several types of 4'-thionucleosides as potential anticancer agents. Detailed studies on the mechanism of action of 4'-thiothymidine are also presented.
