16975-78-3

Basic information

• Product Name: bis(acetoxy)iodylbenzene
• Synonyms: bis(acetoxy)iodylbenzene
• CAS NO: 16975-78-3
• Molecular Weight: 338.099
• Mol File: 16975-78-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: bis(acetoxy)iodylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: bis(acetoxy)iodylbenzene(16975-78-3)
• EPA Substance Registry System: bis(acetoxy)iodylbenzene(16975-78-3)

Safety Data

• Hazardous Substances Data: 16975-78-3(Hazardous Substances Data)

Upstream product

• 696-33-3 iodoxybenzene 
• 64-19-7 acetic acid 
• 108-24-7 acetic anhydride 

Downstream Products

• 536-80-1 iodosylbenzene 

Relevant articles and documents

Bidentate Nitrogen-Ligated I(V) Reagents, Bi(N)-HVIs: Preparation, Stability, Structure, and Reactivity

Hypervalent iodine(V) reagents are a powerful class of organic oxidants. While the use of I(V) compounds Dess-Martin periodinane and IBX is widespread, this reagent class has long been plagued by issues of solubility and stability. Extensive effort has been made for derivatizing these scaffolds to modulate reactivity and physical properties but considerable room for innovation still exists. Herein, we describe the preparation, thermal stability, optimized geometries, and synthetic utility of an emerging class of I(V) reagents, Bi(N)-HVIs, possessing datively bound bidentate nitrogen ligands on the iodine center. Bi(N)-HVIs display favorable safety profiles, improved solubility, and comparable to superior oxidative reactivity relative to common I(V) reagents. The highly modular synthesis and in situ generation of Bi(N)-HVIs provides a novel and convenient screening platform for I(V) reagent and reaction development.