169775-23-9

Upstream product

• 25576-97-0 2,3,6-trimethoxytoluene 
• 105103-87-5 5-bromo-2,4-dimethoxy-3-methylphenol 
• 77-78-1 dimethyl sulfate 
• 6248-20-0 2,4-dihydroxy-3-methylbenzaldehyde 
• 135-77-3 1,2,4-trimethoxy-benzene 
• 81574-49-4 2,4-dimethoxy-3-methylbenzoic acid 
• 608-25-3 2-methylbenzene-1,3-diol 
• 7149-92-0 2,4-dimethoxy-3-methylbenzaldehyde 
• 19676-67-6 2,4-dimethoxy-3-methylphenol 
• 518335-54-1 propionic acid 5-bromo-2,4-dimethoxy-3-methylphenyl ester 
• 383187-30-2 propionic acid 2,4-dimethoxy-3-methylphenyl ester 

Downstream Products

• 95306-76-6 2-bromo-3,5,6-trimethoxy-4-methylbenzaldehyde 
• 518335-55-2 1-bromo-2-dichloromethyl-3,4,6-trimethoxy-5-methylbenzene 
• 1000880-10-3 dimethyl 2-(3-(2,4,5-trimethoxy-3-methylphenyl)prop-2-ynyl)malonate 
• 1384864-07-6 C₂₁H₃₃BrO₃Si 
• 1384864-09-8 C₂₄H₃₇NO₄Si 
• 1384864-10-1 C₁₅H₁₇NO₄ 
• 1384864-12-3 C₂₁H₂₃BrO₄ 
• 1384864-13-4 C₂₄H₂₇NO₅ 
• 1384864-14-5 9-(2-(benzyloxy)ethyl)-5,7,8-trimethoxy-6-methyl-2,3-dihydro-1H-pyrrolo[1,2-a]-indol-1-one 
• 1384864-02-1 1-bromo-2-iodo-3,4,6-trimethoxy-5-methylbenzene 
• 1384864-03-2 C₁₃H₁₅BrO₄ 
• 1384864-04-3 C₁₆H₁₉NO₅ 
• 1384864-05-4 C₂₃H₂₅NO₅ 
• 60059-09-8 2,4,5-trimethoxy-3-methylbenzaldehyde 

Relevant academic research and scientific papers

Catalytic Asymmetric Crotylation of Aldehydes: Application in Total Synthesis of (-)-Elisabethadione

A new, highly efficient Lewis base catalyst for a practical enantio- and diastereoselective crotylation of unsaturated aldehydes with E- and Z-crotyltrichlorosilanes has been developed. The method was employed as a key step in a novel asymmetric synthesis of bioactive serrulatane diterpene (-)-elisabethadione. Other strategic reactions for setting up the stereogenic centers included anionic oxy-Cope rearrangement and cationic cyclization. The synthetic route relies on simple, high yielding reactions and avoids use of protecting groups or chiral auxiliaries.

Formal synthesis of 7-methoxymitosene and synthesis of its analog via a key PtCl2-catalyzed cycloisomerization

A formal synthesis of 7-methoxymitosene is achieved via a key platinum-catalyzed cycloisomerization. The precursor for the Pt catalysis, a fully functionalized benzene intermediate, was prepared via a regioselective electrophilic bromination followed by a

Gold(I)-catalyzed intramolecular [4+2] cycloadditions of arylalkynes or 1,3-enynes with alkenes: Scope and mechanism

The cyclizations of enynes substituted at the alkyne gives products of formal [4+2] cyclization with Au(I) catalysts. 1,8-Dien-3-ynes cyclize by a 5-exo-dig pathway to form hydrindanes. 1,6-Enynes with an aryl ring at the alkyne give 2,3,9,9a-tetrahydro-1

Stereocontrolled synthesis of C-arylglycosides applied to the south west fragment of the antibiotic kendomycin

A nine step synthesis of the southwest fragment 3 of the antibiotic kendomycin (1) is reported. The tetrahydropyran ring is prepared in a highly stereocontrolled and efficient sequence. The key step concerns an anti-aldol reaction using chiral ketone 10. C-Aryl glycoside 3 exhibits atropisomerism and the relative configuration around its tetrahydropyran ring was established by NOE experiments.

Biaryl formation using the Suzuki protocol: Considerations of base, halide, and protecting group

The generation of aryl anions prior to quenching with a trialkyl berate has been shown to be sensitive to the composition of the aryl substrate. Aryl iodides containing remote benzyl ether substituents undergo trans-metallation with sec-BuLi to cleanly give the desired aryl anions whereas the corresponding bromides afford appreciable quantities of dianionic intermediates. The aryl boronic acids derived from alkylation of these anions subsequently undergo a palladium mediated coupling with aryl halides to provide good yields of the desired biaryls. Copyright (C) 1996 Elsevier Science Ltd.