1698-55-1

Basic information

• Product Name: 4-chloro-1,2-dihydro-1-phenylpyridazine-3,6-dione
• Synonyms: 4-chloro-1,2-dihydro-1-phenylpyridazine-3,6-dione;4-Chloro-1,2-dihydro-1-phenyl-3,6-pyridazinedione;4-CHLORO-3-HYDROXY-1-PHENYL-6-PYRIDAZONE;5-chloro-2-phenyl-1H-pyridazine-3,6-dione
• CAS NO: 1698-55-1
• Molecular Formula: C₁₀H₇ClN₂O₂
• Molecular Weight: 222.62778
• EINECS: 216-919-7
• Mol File: 1698-55-1.mol
• Article Data: 0

Chemical Properties

• Melting Point: 255-256 °C
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.48g/cm³
• Refractive Index: 1.66
• PKA: 7.07±0.40(Predicted)
• CAS DataBase Reference: 4-chloro-1,2-dihydro-1-phenylpyridazine-3,6-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-1,2-dihydro-1-phenylpyridazine-3,6-dione(1698-55-1)
• EPA Substance Registry System: 4-chloro-1,2-dihydro-1-phenylpyridazine-3,6-dione(1698-55-1)

Safety Data

• Hazardous Substances Data: 1698-55-1(Hazardous Substances Data)

Usage

Description

4-chloro-1,2-dihydro-1-phenylpyridazine-3,6-dione, commonly known as phenytoin, is a chemical compound that serves as an anticonvulsant medication. It is effective in treating and preventing seizures by stabilizing the electrical activity in the brain, thereby preventing the rapid and excessive firing of nerve cells that can lead to seizures. Phenytoin also has applications in the treatment of certain types of irregular heartbeats and can be used prophylactically to prevent seizures following brain surgery. It is administered orally or intravenously and is available in both brand-name and generic forms. While phenytoin is effective in controlling seizures, it can have side effects such as dizziness, drowsiness, and rash, and should be used with caution in individuals with liver or kidney disease.

Uses

Used in Pharmaceutical Industry:
4-chloro-1,2-dihydro-1-phenylpyridazine-3,6-dione is used as an anticonvulsant medication for the treatment and prevention of seizures. It is effective in stabilizing the electrical activity in the brain and preventing the rapid, excessive firing of nerve cells that can cause seizures.
Used in Cardiology:
4-chloro-1,2-dihydro-1-phenylpyridazine-3,6-dione is used in the treatment of certain types of irregular heartbeats, helping to regulate heart rhythm and prevent complications associated with arrhythmias.
Used in Neurosurgery:
4-chloro-1,2-dihydro-1-phenylpyridazine-3,6-dione is used prophylactically to prevent seizures following brain surgery, reducing the risk of postoperative complications and promoting recovery.

InChI:InChI=1/C10H7ClN2O2/c11-8-6-9(14)13(12-10(8)15)7-4-2-1-3-5-7/h1-6H,(H,12,15)

Upstream product

• 96-02-6 2-chloromaleic anhydride 
• 64-19-7 acetic acid 
• 100-63-0 phenylhydrazine 

Downstream Products

• 92253-37-7 6-chloro-5-morpholino-2-phenyl-3-pyridazinone 
• 92494-45-6 6-chloro-2-phenyl-5-piperidin-1-yl-2H-pyridazin-3-one 
• 91396-19-9 6-chloro-5-dimethylamino-2-phenyl-2H-pyridazin-3-one 
• 106421-11-8 5-dimethylamino-6-methoxy-2-phenyl-2H-pyridazin-3-one 
• 99072-78-3 5,6-diamino-2-phenyl-2H-pyridazin-3-one 
• 1698-59-5 5-amino-6-chloro-2-phenyl-2H-pyridazin-3-one 
• 1698-58-4 3,4-dichloro-1-phenyl-6-pyridazinone 
• 104094-37-3 5-chloro-6-methoxy-2-phenyl-2H-pyridazin-3-one 
• 96776-74-8 thiophosphoric acid O-(4-chloro-6-oxo-1-phenyl-1,6-dihydro-pyridazin-3-yl) ester O',O''-diethyl ester 
• 92376-30-2 4-morpholino-1-phenyl-1,2-dihydro-pyridazine-3,6-dione