169836-50-4

Upstream product

• 61236-87-1 allyl 2,4,6-tri-O-benzyl-α-D-galactopyranoside 
• 130177-78-5 O-(2-O-Acetyl-3,4,6-tri-O-benzyl-α-D-galactopyranosyl) trichloroacetimidate 
• 402578-80-7 allyl 2-acetamido-2-deoxy-4,6-di-O-pivaloyl-β-D-galactopyranosyl-(1->3)-2,4,6-tri-O-benzyl-α-D-galactopyranoside 
• 10378-06-0 2-methyl-(3,4,6-tri-O-acetyl-1,2-dideoxy-α-D-glucopyranoso)[1,2-d]-2-oxazoline 
• 402578-76-1 allyl 2-acetamido-2-deoxy-3,6-di-O-pivaloyl-β-D-glucopyranosyl-(1->3)-2,4,6-tri-O-benzyl-α-D-galactopyranoside 
• 402578-68-1 allyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl-(1->3)-2,4,6-tri-O-benzyl-α-D-galactopyranoside 
• 402578-72-7 allyl 2-acetamido-2-deoxy-β-D-glucopyranosyl-(1->3)-2,4,6-tri-O-benzyl-α-D-galactopyranoside 
• 48149-72-0 (2S,3R,4S,5R,6R)-2-Allyloxy-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol 
• 183954-76-9 allyl 2,4,6-tri-O-benzyl-3-O-(4-methoxybenzyl)-α-D-galactopyranoside 
• 183954-75-8 allyl 3-O-<(p-methoxyphenyl)methyl>-α-D-galactopyranoside 

Downstream Products

• 402578-89-6 allyl 3,4,6-tri-O-benzyl-β-D-galactopyranosyl-(1->3)-2-acetamido-4,6-O-benzylidene-2-deoxy-β-D-galactopyranosyl-(1->3)-2,4,6-tri-O-benzyl-α-D-galactopyranoside 
• 169836-51-5 allyl 3-O-<2-acetamido-2-deoxy-3-O-(3,4,6-tri-O-benzyl-β-D-galactopyranosyl)-β-D-galactopyranosyl>-2,4,6-tri-O-benzyl-α-D-galactopyranoside 

Relevant academic research and scientific papers

Oligosaccharides related to tumor-associated antigens. Part 3. Synthesis of the propyl glycosides of the trisaccharide β-D-Galp-(1 → 3)-β-D-GalpNAc-(1 → 3)-α-D-Galp and of the tetrasaccharide α-L-Fucp-(1 → 2)-β-D-Galp-(1 → 3)-β-D-GalpNAc-(1 → 3)-α-D-Galp,

The synthesis of the trisaccharide β-D-Galp-(1 → 3)-β-D-GalpNAc-(1 → 3)-α-D-Galp-1-OPr (2) and of the tetrasaccharide α-L-Fucp-(1 → 2)-β-D-Galp-(1 → 3)-β-D-GalpNAc-(1 → 3)-α-D-Galp-1-OPr (3), starting from the disaccharidic dihydrooxazole donor 5, is desc

Improvement of the synthesis of immunological carbohydrate vaccines containing the tumour associate antigen CaMBr1

The simplified synthesis of a portion of Globo-H hexasaccharide, a saccharide antigen overexpressed by breast cancer cells, and its conjugation to two different immunogenic proteins are described. The conjugated vaccines, evaluated in a preclinical model, showed good immunogenic potential.