61236-87-1Relevant articles and documents
Improvement of the synthesis of immunological carbohydrate vaccines containing the tumour associate antigen CaMBr1
Lay, Luigi,Panza, Luigi,Poletti, Laura,Prosperi, Davide,Canevari, Silvana,Perico, Maria Elisa
, p. 4331 - 4336 (2007/10/03)
The simplified synthesis of a portion of Globo-H hexasaccharide, a saccharide antigen overexpressed by breast cancer cells, and its conjugation to two different immunogenic proteins are described. The conjugated vaccines, evaluated in a preclinical model, showed good immunogenic potential.