61236-87-1

Upstream product

• 81713-32-8 allyl 3,4-O-isopropylidene-α-D-galactopyranoside 
• 81713-35-1 allyl 2,6-di-O-benzyl-3-O-(2-methoxyethoxy)methyl-α-D-galactopyranoside 
• 81713-34-0 Allyl 2,6-di-O-benzyl-3,4-O-isopropylidene-α-D-galactopyranoside 
• 37111-91-4 allyl 2,6-di-O-benzyl-α-D-galactopyranoside 
• 100-39-0 benzyl bromide 
• 48149-72-0 (2S,3R,4S,5R,6R)-2-Allyloxy-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol 
• 183954-75-8 allyl 3-O-<(p-methoxyphenyl)methyl>-α-D-galactopyranoside 
• 183954-76-9 allyl 2,4,6-tri-O-benzyl-3-O-(4-methoxybenzyl)-α-D-galactopyranoside 
• 81713-37-3 allyl 2,4,6-tri-O-benzyl-3-O-(2-methoxyethoxy)methyl-α-D-galactopyranoside 

Downstream Products

• 117758-94-8 allyl O-(2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl)-(1->3)-2,4,6-tri-O-benzyl-α-D-galactopyranoside 
• 88862-56-0 allyl O-(2,3-di-O-benzoyl-4,6-di-O-benzyl-β-D-galactopyranosyl)-(1<*>3)-2,4,6-tri-O-benzyl-α-D-galactopyranoside 
• 106238-71-5 allyl O-(2-O-benzoyl-4,6-di-O-benzyl-3-O-tert-butyldimethylsilyl-β-D-glactopyranosyl)-(1<*>3)-2,4,6-tri-O-benzyl-α-D-galactopyranoside 
• 106238-72-6 allyl O-<2-O-benzoyl-4,6-di-O-benzyl-3-O-(tetrahydro-2-pyranyl)-β-D-glactopyranosyl>-(1<*>3)-2,4,6-tri-O-benzyl-α-D-galactopyranoside 
• 106238-73-7 allyl O-(2-O-benzoyl-3-O-(3-benzoylpropionyl)-4,6-di-O-benzyl-β-D-galactopyranosyl)-(1<*>3)-2,4,6-tri-O-benzyl-α-D-galactopyranoside 
• 106238-79-3 allyl O-(2,3-di-O-benzoyl-4,6-di-O-benzyl-β-D-galactopyranosyl)-(1<*>3)-O-(2-O-benzoyl-4,6-di-O-benzyl-β-D-galactopyranosyl)-(<1*>3)-2,4,6-tri-O-benzyl-α-D-galactopyranoside 
• 169836-50-4 allyl 2-O-acetyl-3,4,6-tri-O-benzyl-β-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-4,6-di-O-pivaloyl-β-D-galactopyranosyl-(1->3)-2,4,6-tri-O-benzyl-α-D-galactopyranoside 
• 37111-85-6 2,4,6-Tri-O-benzyl-α-D-galactose 
• 173068-11-6 allyl 3-O-(2-acetamido-3-O-acetyl-2-deoxy-4,6-di-O-pivaloyl-β-D-galactopyranosyl)-2,4,6-tri-O-benzyl-α-D-galactopyranoside 
• 183239-82-9 (2S,4aR,6S,7R,8R,8aS)-6-((2S,3R,4S,5S,6R)-2-Allyloxy-3,5-bis-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-4-yloxy)-8-benzoyloxy-2-methyl-7-(2,2,2-trichloro-ethoxycarbonylamino)-hexahydro-pyrano[3,2-d][1,3]dioxine-2-carboxylic acid methyl ester 
• 402578-68-1 allyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl-(1->3)-2,4,6-tri-O-benzyl-α-D-galactopyranoside 
• 169836-51-5 allyl 3-O-<2-acetamido-2-deoxy-3-O-(3,4,6-tri-O-benzyl-β-D-galactopyranosyl)-β-D-galactopyranosyl>-2,4,6-tri-O-benzyl-α-D-galactopyranoside 
• 402578-72-7 allyl 2-acetamido-2-deoxy-β-D-glucopyranosyl-(1->3)-2,4,6-tri-O-benzyl-α-D-galactopyranoside 
• 402578-76-1 allyl 2-acetamido-2-deoxy-3,6-di-O-pivaloyl-β-D-glucopyranosyl-(1->3)-2,4,6-tri-O-benzyl-α-D-galactopyranoside 

Relevant academic research and scientific papers

Improvement of the synthesis of immunological carbohydrate vaccines containing the tumour associate antigen CaMBr1

The simplified synthesis of a portion of Globo-H hexasaccharide, a saccharide antigen overexpressed by breast cancer cells, and its conjugation to two different immunogenic proteins are described. The conjugated vaccines, evaluated in a preclinical model, showed good immunogenic potential.

"STANDARDIZED INTERMEDIATES" FOR OLIGOSACCHARIDE SYNTHESIS. PRECURSORS OF D-GALACTOPYRANOSE RESIDUES HAVING CHAIN EXTENSION AT POSITION 3, OR POSITIONS 3 AND 2

A series of 2-O-benzoyl-4,6-di-O-benzyl-α-D-galactopyranosyl halides carrying either a second benzoyl group (8a, 12a) or a selectively removable, temporary protecting group (8b-d, 12b) at position 3 was synthesized from allyl α-D-galactopyranoside (1).The