169905-33-3Relevant articles and documents
Thiazole-Based Stereoselective Routes to Leucine and Phenylalanine Hydroxyethylene Dipeptide Isostere Inhibitors of Renin and HIV-1 Aspartic Protease
Dondoni, Alessandro,Perrone, Daniela,Semola, M. Teresa
, p. 7927 - 7933 (2007/10/03)
A new synthesis of hydroxyethylene dipeptide isosteres for Leu-Leu and Phe-Phe in their γ-lactone form 1a and 1b employing β-amino-α-hydroxy aldehydes with singly and doubly protected nitrogen has been developed.These key intermediates, which are availabl