169940-41-4Relevant academic research and scientific papers
(S)-13-[(dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16,21- dimetheno-1H,13H-dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecene- 1,3(2H)-dione (LY333531) and related analogues: Isozyme selective inhibitors of protein kinase Cβ
Jirousek, Michael R.,Gillig, James R.,Gonzalez, Cecile M.,Heath, William F.,McDonald III, John H.,Neel, David A.,Rito, Christopher J.,Singh, Upinder,Stramm, Lawrence E.,Melikian-Badalian, Anita,Baevsky, Matthew,Ballas, Lawrence M.,Hall, Steven E.,Winneroski, Leonard L.,Faul, Margaret M.
, p. 2664 - 2671 (1996)
Protein kinase C (PKC) is a family of closely related serine and threonine kinases. Overactivation of some PKC isozymes has been postulated to occur in several disease states, including diabetic complications. Selective inhibition of overactivated PKC iso
