170080-05-4

Basic information

• Product Name: (4S,5S)-4,5-diphenyl-2-oxazolidinone
• Synonyms: (4S,5S)-4,5-diphenyl-2-oxazolidinone
• CAS NO: 170080-05-4
• Molecular Weight: 239.274
• Mol File: 170080-05-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (4S,5S)-4,5-diphenyl-2-oxazolidinone(CAS DataBase Reference)
• NIST Chemistry Reference: (4S,5S)-4,5-diphenyl-2-oxazolidinone(170080-05-4)
• EPA Substance Registry System: (4S,5S)-4,5-diphenyl-2-oxazolidinone(170080-05-4)

Safety Data

• Hazardous Substances Data: 170080-05-4(Hazardous Substances Data)

Usage

General Description

(4S,5S)-4,5-diphenyl-2-oxazolidinone is a chemical compound with the molecular formula C15H13NO2. It is a chiral oxazolidinone derivative that is commonly used as a catalyst in organic synthesis. The compound has a unique structure with a five-membered heterocyclic ring containing an oxygen and a nitrogen atom. It is known for its ability to catalyze various asymmetric reactions, making it an important tool in the field of organic chemistry. Its stereochemistry and molecular arrangement provide it with specific catalytic properties, which make it useful in the production of pharmaceuticals and other fine chemicals. (4S,5S)-4,5-diphenyl-2-oxazolidinone has been the subject of numerous research studies and is valued for its role in facilitating the creation of chiral molecules with high selectivity.

Upstream product

• 97-72-3 2-Methylpropionic anhydride 
• 19190-95-5 rel-(4R,5R)-4,5-diphenyloxazolidin-2-one 
• 103-30-0 (E)-1,2-diphenyl-ethene 
• 51-79-6 urethane 
• 77789-91-4 (1S,2S,1'S)-2-(1'-phenylethyl)amino-1,2-diphenylethanol 
• 2325-10-2 (S,S)-hydrobenzoin 
• 100-52-7 benzaldehyde 
• 1689-71-0 cis-1,2-diphenyloxirane 
• 450370-71-5 (4S,5S,1'S)-N-(1'-phenylethyl)-4,5-diphenyl-2-oxazolidinone 
• 259539-62-3 (4S,5S)-3-Benzoyl-4,5-diphenyl-oxazolidin-2-one 

Downstream Products

• 259539-75-8 ((1S,2S)-2-Hydroxy-1,2-diphenyl-ethyl)-carbamic acid tert-butyl ester 
• 530-36-9 (1S,2S)-2-amino-1,2-diphenylethanol 
• 253350-13-9 (4S,5S)-2-Oxo-4,5-diphenyl-oxazolidine-3-carboxylic acid tert-butyl ester 

Relevant articles and documents

Copper-Catalyzed Enantioselective Reductive Cross-Coupling of Aldehydes and Imines

A copper-catalyzed enantioselective reductive cross-coupling using aromatic aldehydes and imines, producing chiral β-amino alcohols, is described. The catalytic formation of enantioenriched chiral α-alkoxyalkylcopper(I) species from aromatic aldehydes and the subsequent reaction with imine electrophiles are attractive features of this protocol.

Chemoselective debezylation of the N-1-phenylethyl group in 2-oxazolidinones by the anisole-methanesulfonic acid system

The chemoselective removal of N-1-phenylethyl group in 2-oxazolidinones by the anisole-methanesulfonic acid system was investigated. Optically active 4,5-cis- and 4,5-trans-diphenyl-2-oxazolidinones (1a-d) were easily synthesized from dl-stilbene oxides (trans- and cis-7a) using this debenzylation.

Expanding Synthetic Utilities of Asymmetric Dihydroxylation Reaction: Conversion of syn-Diols to syn-Amino Alcohols

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