170102-27-9

Upstream product

• 98-88-4 benzoyl chloride 
• 545387-38-0 N-tert-butyl-N'-phenyloxycarbonylhydrazine 
• 1885-14-9 phenyl chloroformate 

Downstream Products

• 403739-79-7 C₁₈H₁₉Cl₂N₃O₂ 
• 403739-77-5 C₁₈H₂₀FN₃O₂ 
• 403739-78-6 C₁₉H₂₃N₃O₃ 
• 403739-88-8 C₁₈H₂₀ClN₃O₂ 
• 403739-76-4 C₁₈H₂₁N₃O₂ 
• 99981-48-3 N'-t-butyl-N'-benzoylhydrazine 

Relevant academic research and scientific papers

A Convenient Synthesis of Novel N′-tert-Butyl-N′-Substituted Benzoyl-N-(Substituted Phenyl)aminocarbonylhydrazines and Their Derivatives

N-tert-butyl-N-substituted benzoylhydrazines were prepared in two convenient procedures with good yields, subsequent reaction with substituted phenylisocyanates in 1,2-dichloroethane provided a series of novel N′-tert-butyl-N‰-substituted benzoyl-N-(substituted phenyl)aminocarbonylhydrazines. Further treatment with oxalyl chloride gave their derivatives in good yields. The title compounds exhibit moderate larvicidal activities and anticancer activities.

Alkylgermasesquioxide Derivatives of tert-Butyl-diacylhydrazines

N-tert-Butyl-N-benzoylhydrazine was synthesized by a new method. Its condensation and the condensation of its N,N'-isomer with 3-(trichlorogermyl)propionyl chloride provided N-tert-butyl-N'-(3-trichlorogermyl)propionyl-N-benzoylhydrazine or its N,N,N'-isomer, respectively, in good yields. Subsequent hydrolysis of the trichlorogermyl compounds using saturated sodium carbonate yielded the corresponding germasesquioxide derivatives that have good solubility in organic solvents. The structures of these compounds were confirmed by 1H NMR, IR, MS, and elemental analysis. The hydrolysis of organogermanium trichloride was studied, and the elimination of HGeCl3 was observed when the basicity was too high (pH>10).

New Reactions of N-t-Butyl-N-Benzohydrazine with Triphosgene

N-tert-Butyl-N-benzoylhydrazine was prepared in a new and convenient procedure with good yield. Triphosgene underwent reaction with three equivalents of N-t-butyl-N-benzoylhydrazine using six equivalents of triethylamine as a base to yield the cyclic tetramer of N-t-butyl-N-isocyanatobenzoylamide. Treatment of triphosgene with three equivalents of N-t-butyl-N-benzoylhydrazine either in the presence of three equivalents of triethylamine or in the absence of triethylamine afforded the cyclic pentamer of isocyanate, from which tert-butyl is eliminated.