170119-33-2 Usage
Uses
Used in Pharmaceutical Industry:
[1-(4-CHLORO-PHENYL)-2-PYRROLIDIN-1-YL-ETHYL]-METHYL-AMINE is used as a key intermediate in the synthesis of various drugs and pharmaceuticals. Its specific structure and properties allow it to be incorporated into the development of new medications, enhancing their efficacy and targeting specific biological pathways.
Used in Organic Synthesis:
In the field of organic synthesis, [1-(4-CHLORO-PHENYL)-2-PYRROLIDIN-1-YL-ETHYL]-METHYL-AMINE serves as a valuable building block for the creation of more complex chemical compounds. Its unique structure facilitates its use in the assembly of novel molecules with potential applications in various industries, including materials science, agrochemicals, and specialty chemicals.
Used in Drug Development:
[1-(4-CHLORO-PHENYL)-2-PYRROLIDIN-1-YL-ETHYL]-METHYL-AMINE is utilized in drug development as a precursor to design and synthesize new pharmaceutical agents. Its chemical properties enable it to be modified and combined with other molecules to create innovative drugs with improved therapeutic profiles and targeted effects on specific diseases or conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 170119-33-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,0,1,1 and 9 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 170119-33:
(8*1)+(7*7)+(6*0)+(5*1)+(4*1)+(3*9)+(2*3)+(1*3)=102
102 % 10 = 2
So 170119-33-2 is a valid CAS Registry Number.
InChI:InChI=1/C13H19ClN2/c1-15-13(10-16-8-2-3-9-16)11-4-6-12(14)7-5-11/h4-7,13,15H,2-3,8-10H2,1H3
170119-33-2Relevant academic research and scientific papers
Synthesis and κ binding affinity of 1-(pyrrolidin-1-ylmethyl)-2-(N-methyl)-4--1,2,3,4-tetrahydroisoquinolin-3(2H)-ones
Pinna, G. A.,Gavini, E.,Cignarella, G.,Scolastico, S.,Fadda, P.
, p. 515 - 520 (2007/10/02)
Diastereomeric forms of 1-(pyrrolidin-1-ylmethyl)-2-(N-methyl)-4--1,2,3,4-tetrahydroisoquinolin-3-(2H)-ones 3a and its chloro analog 3c were synthesized.Compounds 3a,c are related to the κ-selective opiate ICI 199441 1 by linking the benzylic CH2 to the ortho position of the phenyl in 1.Compared with morphine, these compounds had lost in κ and μ affinities; only cis-3a showed a modest κ affinity. 1-Pyrrolidin-1-ylmethyl-N--1,2,3,4-tetrahydroisoquinoline 2, which is also a cyclic congener of 1, was reported to display high κ and μ affinity, and so a conformational study was undertaken on 1, 2 and 3a.This showed that while active 2 extensively superposed on 1, 3a assumes another geometry which does now allow a fit with the pharmacophoric moieties of 1 and 2. tetrahydroisoquinolin-3(2H)-one / κ-opiate receptor / rigid congener
