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CAS

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170147-60-1

3-chloro-4-{[1-(5-phenylpentyl)-1H-indol-5-yl]oxy}benzonitrile is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 170147-60-1 Structure

  • Basic information

    1. Product Name: 3-chloro-4-{[1-(5-phenylpentyl)-1H-indol-5-yl]oxy}benzonitrile
    2. Synonyms: 3-chloro-4-{[1-(5-phenylpentyl)-1H-indol-5-yl]oxy}benzonitrile
    3. CAS NO:170147-60-1
    4. Molecular Formula:
    5. Molecular Weight: 414.934
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 170147-60-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 3-chloro-4-{[1-(5-phenylpentyl)-1H-indol-5-yl]oxy}benzonitrile(CAS DataBase Reference)
    10. NIST Chemistry Reference: 3-chloro-4-{[1-(5-phenylpentyl)-1H-indol-5-yl]oxy}benzonitrile(170147-60-1)
    11. EPA Substance Registry System: 3-chloro-4-{[1-(5-phenylpentyl)-1H-indol-5-yl]oxy}benzonitrile(170147-60-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 170147-60-1(Hazardous Substances Data)

170147-60-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 170147-60-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,0,1,4 and 7 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 170147-60:
(8*1)+(7*7)+(6*0)+(5*1)+(4*4)+(3*7)+(2*6)+(1*0)=111
111 % 10 = 1
So 170147-60-1 is a valid CAS Registry Number.

170147-60-1Downstream Products

170147-60-1Relevant articles and documents

A novel class of inhibitors for human steroid 5α-reductase: Synthesis and biological evaluation of indole derivatives. II

Igarashi, Susumu,Inami, Hiroshi,Hara, Hiromu,Fujii, Masahiro,Koutoku, Hiroshi,Oritani, Hiroyuki,Mase, Toshiyasu

, p. 382 - 388 (2007/10/03)

In a search for novel nonsteroidal inhibitors of human prostatic 5α- reductase, we found a new series of indole derivatives that showed potent inhibitory activities for the human enzyme. Among them, 4-[(1-benzyl-1- Hindol-5-yl)oxy]-3-chlorobenzoic acid (2d, YM-32906) showed more potent inhibitory activity than finasteride with an IC50 value of 0.44 nM. 3- Chloro-4-{[1-(4-phenoxybenzyl)-1H-indol-5-yl]oxy}benzoic acid (2m) showed inhibitory activities for both human and rat prostatic 5α-reductase with IC50 values of 2.1 and 73 nM, respectively. The synthesis and structure- activity relationships of these indole derivatives are presented.

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