170238-97-8

Upstream product

• 28030-16-2 3-(4-methoxyphenyl)-2-oxopropanoic acid 
• 284663-39-4 N,N-dimethyl 2-methoxycarbonyl-3-iodo-4-(p-methoxyphenyl)-1H-pyrrole-1-sulfonamide 
• 284663-29-2 N,N-dimethyl 2-methoxycarbonyl-3,4-bis(trimethylsilyl)-1H-pyrrole-1-sulfonamide 
• 41564-67-4 (E)-1,3-bis(4-methoxyphenyl)-2-propene-1-one 
• 55097-58-0 [3-(4-methoxyphenyl)oxiran-2-yl]-(4-methoxyphenyl)methanone 
• 1337927-65-7 (E)-4,4'-(1-nitroethene-1,2-diyl)bis(4-methoxybenzene) 
• 59019-40-8 1-[(1Z)-2-bromo-2-nitroethenyl]-4-methoxybenzene 
• 3179-10-0 1-methoxy-4-(2-nitro-vinyl)-benzene 
• 170238-95-6 4,5-bis(4-methoxyphenyl)isoxazole 
• 284663-53-2 N,N-dimethyl 2-methoxycarbonyl-3,4-bis(p-methoxyphenyl)-1H-pyrrole-1-sulfonamide 
• 284663-63-4 N,N-dimethyl 2-methoxycarbonyl-3-trimethylsilyl-4-(p-methoxyphenyl)-1H-pyrrole-1-sulfonamide 
• 284663-33-8 N,N-dimethyl 2-methoxycarbonyl-3-trimethylsilyl-4-iodo-1H-pyrrole-1-sulfonamide 
• 170238-94-5 3,4-bis(4-methoxyphenyl)-1H-pyrrole-2-carboxylic acid methyl ester 
• 2632-13-5 2-Bromo-4'-methoxyacetophenone 

Downstream Products

• 144398-24-3 3,7,8-tris(4-hydroxyphenyl)-1H-pyrrolo[2,1-c][1,4]oxazin-1-one 

Relevant academic research and scientific papers

Synthesis of lamellarin R, lukianol A, lamellarin O and their analogues

Three lamellarin alkaloids type III (lamellarin R, lukianol A and lamellarin O) were synthesized using the Barton-Zard reaction as a key step to construct the central pyrrole core. Some of their corresponding 4-benzoyl and 5-phenyl substituted pyrrole ana

Synthesis of simple 3,4-diarylpyrrole-2,5-dicarboxylic acids and lukianol A by oxidative condensation of 3-arylpyruvic acids with ammonia

Several derivatives of 3,4-diaryl- and 3,4-diindolylpyrrole-2,5- dicarboxylic acids including lycogalic acid A and two Halomonas metabolites were synthesized by oxidative dimerization of arylpyruvic acids or arylpyruvates in the presence of ammonia. The r

Biomimetic syntheses of lamellarin and lukianol-type alkaloids

The formation of 3,4-diarylpyrrole-2,5-dicarboxylic acids from arylpyruvic acids and 2-arylethylamines was used as a key step for the synthesis of several marine pyrrole alkaloids. The utility of this method is illustrated through the development of synth

Highly regioselective synthesis of 2,3,4-trisubstituted 1H-pyrroles: A formal total synthesis of lukianol A

A combined use of α-lithiation and nucleophilic substitutions of N,N- dimethyl 3,4-bis(trimethylsilyl)-1H-pyrrole-1-sulfonamide 8c led to several 2-substituted 3,4-bis(trimethylsilyl)-1H-pyrrole-1-sulfonamides. Utilizing the β-effect of a trimethylsilyl group, a highly regioselective synthesis of 2,3,4-trisubstituted 1H-pyrroles 23 and 34 was accomplished. The marine natural product lukianol A (3) was prepared utilizing this strategy.