284663-53-2

Upstream product

• 5720-07-0 4-methoxyphenylboronic acid 
• 284663-39-4 N,N-dimethyl 2-methoxycarbonyl-3-iodo-4-(p-methoxyphenyl)-1H-pyrrole-1-sulfonamide 
• 284663-63-4 N,N-dimethyl 2-methoxycarbonyl-3-trimethylsilyl-4-(p-methoxyphenyl)-1H-pyrrole-1-sulfonamide 
• 284663-29-2 N,N-dimethyl 2-methoxycarbonyl-3,4-bis(trimethylsilyl)-1H-pyrrole-1-sulfonamide 
• 284663-33-8 N,N-dimethyl 2-methoxycarbonyl-3-trimethylsilyl-4-iodo-1H-pyrrole-1-sulfonamide 
• 278167-17-2 N-N-dimethyl 3,4-bis(trimethylsilyl)-1H-pyrrole-1-sulfonamide 

Downstream Products

• 170238-96-7 methyl 3,4-bis(4-methoxyphenyl)-1-[2-(4-methoxyphenyl)-2-oxoethyl]-1H-pyrrole-2-carboxylate 
• 170238-97-8 1H-3,7,8-tris(4-methoxyphenyl)pyrrolo<2,1-c><1,4>-oxazin-1-one 
• 144398-24-3 3,7,8-tris(4-hydroxyphenyl)-1H-pyrrolo[2,1-c][1,4]oxazin-1-one 
• 170238-94-5 3,4-bis(4-methoxyphenyl)-1H-pyrrole-2-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Highly regioselective synthesis of 2,3,4-trisubstituted 1H-pyrroles: A formal total synthesis of lukianol A

A combined use of α-lithiation and nucleophilic substitutions of N,N- dimethyl 3,4-bis(trimethylsilyl)-1H-pyrrole-1-sulfonamide 8c led to several 2-substituted 3,4-bis(trimethylsilyl)-1H-pyrrole-1-sulfonamides. Utilizing the β-effect of a trimethylsilyl group, a highly regioselective synthesis of 2,3,4-trisubstituted 1H-pyrroles 23 and 34 was accomplished. The marine natural product lukianol A (3) was prepared utilizing this strategy.