17024-02-1Relevant articles and documents
Phenanthrene Synthesis by Palladium(II)-Catalyzed γ-C(sp2)-H Arylation, Cyclization, and Migration Tandem Reaction
Gou, Bo-Bo,Yang, Hui,Sun, Huai-Ri,Chen, Jie,Wu, Junliang,Zhou, Ling
supporting information, p. 80 - 84 (2019/01/11)
Phenanthrene is an important structural motif in chemistry and materials science, and many synthetic routes have been developed to construct its skeleton. However, synthesis of unsymmetric phenanthrenes remains a challenge. Here, an efficient one-pot tandem reaction for the preparation of phenanthrenes via sequential γ-C(sp2)-H arylation, cationic cyclization, dehydration, and 1,2-migration was developed. A wide range of symmetric and unsymmetric phenanthrenes with diversified functional groups were synthesized with good to excellent yields.
A 9, 10 - disubstituted philippine apperception compound synthesis method
-
Paragraph 0041-0050, (2019/03/23)
The invention discloses a 9, 10 - disubstituted philippine apperception compound synthesis method, the method specifically is: the method to the molecular formula is And of the compound as a raw material of the formula Aryl halides, amino acid, silver salt and two price arrowheads catalyst prepared under the effect of the molecule Of 9, 10 - disubstituted philippine apperception composition; the invention through divalent palladium are the catalyst, through the amino acid as a transient guide base of the C (sp2 ) - H arylation and cascade reaction, a step construction 9, 10 - disubstituted philippine apperception composition, prepared by the yield of 9, 10 - disubstituted [...] derivatives; the operation of the invention is simple, easy availability of raw materials, the raw material cost, and the use of efficient reaction C - H arylation strategy effectively reduce the halide or to the use of halide, transient guide-based usage does make the reaction more simple, more economic.
