170455-86-4Relevant academic research and scientific papers
Aryl Ether Syntheses via Aromatic Substitution Proceeding under Mild Conditions
Ando, Shin,Tsuzaki, Marina,Ishizuka, Tadao
, p. 11181 - 11189 (2020/10/12)
In this study, mild conditions for aromatic substitutions during the syntheses of aryl ethers were developed. In the reaction conditions, the choices of solvent, base, and the sequence for the addition of the reagents proved important. A wide variety of alcohols were used directly as nucleophiles and smoothly reacted with aryl chlorides that possessed either a nitro or a cyano group at either the ortho- or para-position. Controlled experiments we performed suggested that the reaction underwent a charge-transfer process mediated by a combination of DMF and tert-BuOK.
Ultrasound assisted Friedel-Crafts acylation of aromatics using ferric sulphate as catalyst
Sridharan, Anandhi,Gopalakrishnan, Geetha
experimental part, p. 1192 - 1195 (2011/10/18)
The use of ultrasound in the acylation reactions of various aromatics and polyaromatics with different acyl chlorides, in the presence of catalytic amount of ferric sulphate at room temperature, gives good yields of the respective ketones with a short reaction time. A facile and simple synthesis of various aromatic ketones using Friedel-Crafts acylation has been established from the corresponding acid chlorides and aromatic or polyaromatic compounds, respectively under mild reaction conditions with shorter reaction times (30-45 min) and in reasonable yields. This method offers the advantage of low cost and ease of purification of the products because of the small amount of ferric sulphate used in these reactions.
Facile synthesis of pivalophenones by an ultrasound assisted iodine catalysed Friedel-Crafts acylation reaction
Gopalakrishnan, Geetha,Anandhi,Narasimhan
, p. 1197 - 1198 (2007/10/03)
The use of ultrasound in the acylation reactions of various aromatics and heterocyclics with pivaloyl chloride in the presence of catalytic amount of iodine, without any added solvent and at room temperature, gives excellent yields of the respective pivalophenones in a short reaction time.
A facile synthesis of pivalophenones by ultrasound assisted AlCl3 catalysed Friedel-Crafts reaction
Gopalakrishnan, Geetha,Anandhi,Narasimhan
, p. 1194 - 1196 (2007/10/03)
Pivalophenones have been prepared by the acylation reaction of various aromatic and heterocyclic compounds with pivaloyl chloride using AlCl3 as catalyst under sonochemical conditions in a short reaction time and in reasonable yields.
Facile synthesis of 3-(p-alkoxyphenyl)-3-methyl-2-butanones
Gopalakrishnan,Anandhi
, p. 2521 - 2528 (2007/10/02)
A novel procedure for the preparation of 3-(p-hydroxyphenyl)-3-methyl-2-butanone, in excellent yield, is described via a simple AlCl3 catalysed rearrangement of p-ethoxy-pivalophenone. Various 3-(p-alkoxyphenyl)-3-methyl-2-butanones have been s
Novel Synthesis and Insecticideal Activity of MTI-800, Desfluoro MTI-800 and Their Intermediates
Gopalakrishnan, Geetha,Suresh, G.,Anandhi, S.
, p. 363 - 368 (2007/10/03)
A new route to the synthesis of 2-(4-ethoxyphenyl)-2-methyl-5-(3-phenoxyphenyl)pentane (desfluoro MTI-800) and 2-(4-ethoxyphenyl)-2-methyl-5-(4-fluoro-3-phenoxyphenyl)pentane (MTI-800) and the insecticidal activities of these compounds and some of the synthetic intermediates against the tobacco caterpillar Spodoptera litura (F.) is reported.
