103-73-1Relevant articles and documents
1,1,2,2-tetraphenyldisilane as a diversified radical reagent
Yamazaki, Osamu,Togo, Hideo,Matsubayashi, Sou,Yokoyama, Masataka
, p. 1921 - 1924 (1998)
Reactivity of 1,1,2,2-tetraphenyldisilane as a radical reagent in ethanol was studied in reduction of alkyl bromides, addition to olefin and alkylation onto heteroaromatic bases with alkyl bromides. The present organodisilane showed moderate to good reactivities for these three types of radical reactions.
Nanosized ferric hydroxide catalyzed c-o cross-coupling of phenol and halides to generate phenoxy ether
Sun, Hongbin,Sun, Yuanhua,Tian, Xiaohua,Zhao, Yunxia,Qi, Xuan
, p. 6189 - 6191 (2013)
The iron-based catalyst can effectively catalyze the phenolic hydroxyl C-O bond formation reaction to give the corresponding phenoxy ethers. The reaction of phenol and methyl chloroacetate, for example, gives phenoxy acetic acid methyl ester in 98 % yield under the optimal reaction conditions. Among the iron-based catalysts, nanosized ferric hydroxide prepared through sol-gel method gives the best catalytic activity.
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Lubinkowski,McEwen
, p. 4817 (1972)
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Electrogenerated base-promoted synthesis of organic carbonates from alcohols and carbon dioxide
Casadei, Maria Antonietta,Cesa, Stefania,Rossi, Leucio
, p. 2445 - 2448 (2000)
Electrogenerated bases promote the reaction between primary alcohols and carbon dioxide to give organic carbonates in excellent yields. Secondary alcohols are converted in moderate yields, whereas tertiary alcohols and phenols are unreactive. 1,2-Diols give a mixture of both cyclic and linear diand monocarbonates. These latter are intermediates in the reaction pathway leading to the cyclic derivatives.
Synthesis of novel greener functionalized ionic liquids containing appended hydroxyl
Feng, Guo Ren,Peng, Jia Jian,Qiu, Hua Yu,Jiang, Jian Xiong,Tao, Lan,Lai, Guo Qiao
, p. 2671 - 2675 (2007)
Novel "greener" functionalized ionic liquids have been prepared by the reaction of 1,2-epoxy propane and dilute sulfuric acid with [EMIm]Br or [BMIm]Br formed by alkyl bromide (RBr) and 1-methylimidazole. This kind of ionic liquid could be possibly used as green solvent and catalyst, especially as phase-transfer catalyst in organic chemistry (e.g., the synthesis of ethoxybenzene). Their chemical structures were characterized by 1H NMR, 13C NMR, and IR. Copyright Taylor & Francis Group, LLC.
Simple and Rapid Determination of the Activation Parameters of Organic Reactions by Temperature-Dependent NMR Spectroscopy I. Application to Irreversible Reactions
Satoh, Masahiro,Hirota, Minoru
, p. 2031 - 2038 (1996)
A rapid and convenient method for the evaluation of activation enthalpies and entropies of reactions in solutions was contrived. This was realized by the stepwise elevation of the temperature of a reaction system using a variable temperature apparatus of NMR spectrometer. A repetition of rapid collection of FIDs (Free Inductive Decays) at every plateau part of temperature at regular intervals allows us to determine the time-conversion curve, from which the rates at various temperatures were obtained as the first derivatives. Several examples of applications are shown.
Ionic liquids as reagent and reaction medium: Preparation of alkyl aryl ethers
Mohanazadeh, Farajollah,Aghvami, Majid
, p. 47 - 49 (2007)
Room temperature ionic liquid, [bmIm]OH, is used as a green recyclable reaction medium and reagent for the alkylation of phenols in excellent yields. The recovered ionic liquid was reused five to six times with consistent activity.
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Cook
, p. 608 ()
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N-ARYL SULFONAMIDE DERIVATIVES AS VACCINE ADJUVANT
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Page/Page column 101-102, (2021/02/26)
Bis-aryl sulfonamide compounds and methods of using those compounds, e.g., in a method of enhancing or prolonging an immune response, are provided. For example, the compounds may be employed with a vaccine and optionally at least one other adjuvant and/or one or more TLR ligands, at least one MAP kinase inhibitor, or any combination thereof.
Mustard Carbonate Analogues as Sustainable Reagents for the Aminoalkylation of Phenols
Annatelli, Mattia,Trapasso, Giacomo,Salaris, Claudio,Salata, Cristiano,Castellano, Sabrina,Aricò, Fabio
supporting information, p. 3459 - 3464 (2021/05/24)
N,N-dialkyl ethylamine moiety can be found in numerous scaffolds of macromolecules, catalysts, and especially pharmaceuticals. Common synthetic procedures for its incorporation in a substrate relies on the use of a nitrogen mustard gas or on multistep syntheses featuring chlorine hazardous/toxic chemistry. Reported herein is a one-pot synthetic approach for the easy introduction of aminoalkyl chain into different phenolic substrates through dialkyl carbonate (β-aminocarbonate) chemistry. This new direct alcohol substitution avoids the use of chlorine chemistry, and it is efficient on numerous pharmacophore scaffolds with good to quantitative yield. The cytotoxicity via MTT of the β-aminocarbonate, key intermediate of this synthetic approach, was also evaluated and compared with its alcohol precursor.
