170470-96-9

Upstream product

• 130327-74-1 diethyl 2-acetyl-5-deazaisofolate 
• 130327-75-2 di-tert-butyl 5-deazaisofolate 
• 130327-71-8 2-amino-3,4-dihydro-4-oxo-6-nitropyrido<2,3-d>pyrimidine hydrochloride 
• 87597-84-0 di-tert-butyl N-(4-formylbenzoyl)-L-glutamate 
• 56277-36-2 diethyl 4-formylbenzoyl-L-glutamate 
• 130327-72-9 N-(6-Nitro-4-oxo-3,4-dihydro-pyrido[2,3-d]pyrimidin-2-yl)-acetamide 
• 130327-73-0 2-acetamido-6-amino-3,4-dihydro-4-oxopyrido<2,3-d>pyrimidine 
• 91996-79-1 2,6-diamino-3,4-dihydro-4-oxopyrido<2,3-d>pyrimidine 
• 130327-67-2 5-deazaisofolic acid 

Relevant academic research and scientific papers

Synthesis and biological evaluation of 5-deazaisofolic acid, 5-deaza-5,6,7,8-tetrahydroisofolic acid, and their N9-substituted analogues

Prompted by recent disclosures concerning the potent antitumor activities of 5-deaza-5,6,7,8-tetrahydrofolic acid and 5,10-dideaza-5,6,7,8-tetrahydrofolic acid (DDATHF), we have prepared 5-deazaisofolic acid (3a) and 5-deaza-5,6,7,8-tetrahydroisofolic aci