170632-15-2Relevant academic research and scientific papers
Method of treating disorders related to protease-activated receptors-induced cell activation
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, (2008/06/13)
A method of treating a disorder related to cell activation induced by protease-activated receptors. The method includes administering to a subject in need thereof a compound having a pyrazolyl core; an aryl group, via an via an alkylene linker, bonded to 1-N of the pyrazolyl core; a second aryl group fused at 4-C and 5-C of the pyrazolyl core; and a third aryl group bonded directly to 3-C of the pyrazolyl core.
Synthesis of 1-benzyl-3-(5′-hydroxymethyl-2′-furyl)indazole analogues as novel antiplatelet agents
Le,Lien,Huang,Huang,Tsai,Teng,Wu,Cheng,Kuo
, p. 3746 - 3749 (2007/10/03)
1-Benzyl-3-(5′-hydroxymethyl-2′-furyl)indazole (28, YC-1) was selected as the lead compound for systemic structural modification. After screening for antiplatelet activity, SARs of YC-1 analogues were established. Among these potent active derivatives, co
1-Benzyl-3-(substituted aryl)-condensed pyrazole derivatives as inhibitors of platelet aggregation
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, (2008/06/13)
1-Benzyl-3-(substituted aryl) condensed pyrazoles of the general formula (A): wherein, R1 represents H, C1 3 alkyl, halogen, or -OR, in which R represents H or C1 3 alkyl; represents wherein R2/
