170648-35-8

Basic information

• Product Name: 3-(4-chlorophenyl)-5-hydroxy-4,5-dihydroisoxazole
• Synonyms: 3-(4-chlorophenyl)-5-hydroxy-4,5-dihydroisoxazole
• CAS NO: 170648-35-8
• Molecular Weight: 197.621
• Mol File: 170648-35-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-(4-chlorophenyl)-5-hydroxy-4,5-dihydroisoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-chlorophenyl)-5-hydroxy-4,5-dihydroisoxazole(170648-35-8)
• EPA Substance Registry System: 3-(4-chlorophenyl)-5-hydroxy-4,5-dihydroisoxazole(170648-35-8)

Safety Data

• Hazardous Substances Data: 170648-35-8(Hazardous Substances Data)

Upstream product

• 1075-77-0 4-chlorocinnamaldehyde 
• 109-99-9 tetrahydrofuran 
• 15500-74-0 4-chlorobenzonitrile N-oxide 
• 67382-35-8 (2E)-3-(dimethylamino)-1-(4-chlorophenyl)prop-2-en-1-one 

Downstream Products

• 31301-39-0 3-(4-chlorophenyl)-isoxazole 
• 1213268-58-6 C₉H₁₀ClNO₂ 

Relevant articles and documents

Efficient and regioselective synthesis of 5-hydroxy-2-isoxazolines: Versatile synthons for isoxazoles, β-lactams, and γ-amino alcohols

"Chemical Equation Presented" An efficient and highly regioselective protocol was developed for the preparation of 5-hydroxy2-isoxazolines, which have been proved to be versatile synthons for isoxazles, β-hydroxy oximes, and γ-amino alcohols. β-Lactams, commonly embedded in the skeletons of bioactive natural products, were also synthesized in two steps from β-hydroxy oximes, providing a new strategy for the synthesis of this kind of compounds.

Reaction of β-dimethylaminovinyl ketones with hydroxylamine: A simple and useful method for synthesis of 3- and 5-substituted isoxazoles

(Chemical Equation Presented) The regioselective synthesis of 3- and 5-substituted-isoxazoles from the reaction of β-dimethylaminovinyl ketones [R-C(O)CH=CH-NMe2, where R = Ph, MeO-4-C6H4, F-4-C6H4, C